Psyc10 Flashcards

Depressants: -Intoxication -Withdrawal

1
Q

Nonspecific signs of Depressant intoxication.

A
Mood elevation
DEcreased anxiety
Sedation
Behavioral disinhibition
Respiratory depression
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2
Q

Nonspecific signs of Depressant withdrawal.

A

Anxiety
Tremor
Seizures
Insomnia

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3
Q

What are the classes of Depressants.

A

Alcohol
Opioids
Barbiturates
Benzodiazepines

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4
Q

What are the signs of Alcohol intoxication?

A
Emotional lability
Slurred speech
Ataxia
Coma
Blackouts
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5
Q

What are the lab findings associated with alcohol intoxication?

A

Serum gamma-glutamyltransferase (GGT)
-sensitive indicator of alcohol use
Lab AST value twice that of ALT

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6
Q

What is the treatment for Delirium Tremens?

A

Benzodiazepines

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7
Q

What are the signs of Opioid intoxication?

A
Euphoria
Respiratory & CNS depression
DEcreased Gag reflex
Pupillary constriction - "Pinpoint pupils"
Seizures (Overdose)
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8
Q

What is the treatment for Opioid intoxication?

A

Naloxone

Naltrexone

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9
Q

What are the signs of Opioid withdrawal?

A
Sweating
Dilated pupils
Piloerection ("cold turkey)
Fever
Rhinorrhea
Yawning
Nausea/Diarrhea ("flu-like sxs)
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10
Q

What is the treatment for Opiod withdrawal?

A

Long-term support
Methadone
Buprenorphine

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11
Q

What are the signs for Barbituate intoxication?

A

Low safety margin

Marked respiratory depression

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12
Q

What is the treatment for barbituate intoxication?

A

Symptom management:

  • Assist respiration
  • INcreased BP
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13
Q

What are the signs of Barbituate withdrawals?

A

Delirium

Life-Threatening Cardiovascular collapse

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14
Q

What are the sings of Benzodiazepine intoxication?

A

Greater safety margin
Ataxia
Minor respiratory depression

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15
Q

What is the treatment for Benzodiazepine intoxication?

A

Flumazenil (GABA antagonist)

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16
Q

What are the withdrawal symptoms of Benzodiazepines?

A

Sleep disturbance
Depression
Rebound anxiety
Seizure (severe)

17
Q

What depressant has a synergistic with alcohol?

A

Benzodiazepines

18
Q

What conditions are Heroin addicts at an increased risk of?

A
Hapatitis
Abscesses
Overdose
Hemorrhoids
AIDS
RIGHT-SIDED Endocarditis
19
Q

What is the triad for Wernicke-Korsakoff syndrome?

A

*AKA - Wernicke’s encephalopathy”
Confusion
Opthalmoplegia
Ataxia

20
Q

What is Wernicke-Korsakoff syndrome caused by?

A

Thiamine deficiency

21
Q

What is Wernicke-Korsakoff syndrome associated with?

A

Periventricular hemorrhage
Necrosis of MAMILLARY bodies
Cardiomyopathies

22
Q

What is mallory-weiss syndrome?

A

Longitudinal lacerations at the agastroesophageal junction caused by excessive vomiting

often presents with hematesmesis

23
Q

T/F - Mallow-Weiss tears are painful.

A

True

Esophageal varices - NO PAIN

24
Q

When is the onset of Delirium Tremens?

A

2-5 days after last drink

25
Q

How do you treat DTs?

A

Benzodiazepines