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Rheumatology > Psoriasis > Flashcards

Psoriasis Flashcards

1
Q

Presentation

A

Asymmetrical arthropathy of the hands - mainly DIP
Nail changes - pitting, oncholysis, transverse ridging, subungal hyperkeratosis
Skin rash - silvery plaques
Non scarring, improves with sun

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2
Q

Patterns of joint involvement

A
  • asymmetrical oligoarthritis - mainly DIP
  • symmetrical polyarthritis - PIP and MCP
  • DIP arthritis
  • arthritis mutilans
    Spondylitis +/- sacroiliitis
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3
Q

Genetic association

A

HLA B27+ve

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4
Q

Radiologically

A

Early deformity with bone lysis and telescoping of digits –> pencil in a cup

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5
Q

Management

A

Patient education
Physio
OT
Analgesia
NSAIDs
Steroids
DMARDs - methotrexate, sulfasalazine, ciclosporin
Biologics - anti-TNF alpha

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6
Q

Adverse effects of TNF alpha therapy

A

Serious infections - TB!
Haematological malignancy

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Rheumatology (9 decks)

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