Psoriasis Flashcards

1
Q

Psoriasis: generalidades

A
  • enf inmunitaria cronica sistemica
  • prevalencia 2% chile
  • sin diferencia de genero
  • es de adultos jovenes (75% debuta antes de 45 años)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Psoriasis: patogenia

A
  • multifactorial
  • rol importante de TH17
  • region genica importante: PSORS 1
  • cascada inflamatoria a nivel epidermico: vasodilatacion papila, proliferacion queratinocitos basales y migracion de PMN
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Psoriasis: riesgo familiar

A

ambos padres 40%
1 padre 14%
hermano 6%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Psoriasis: factores desencadenantes

A

externos: traumas, quemadura (koebner)
sistemicos: infecciones (45%), vih, estres, embarazo, hipocalcemia, habitos, obesidad, farmacos

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Psoriasis: clinica

A
  • papulas, placas eritemato-descamativas
  • bien delimitadas
  • simetrica
  • superficies extensoras
  • signo auspitz
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Psoriasis: localziaciones especiales

A

1) cuero cabelludo: respeta cara
2) ungueales: predictores de art psoriatica
3) palmoplantar: no sobrepasa palma/planta, en geernal simetricas
4) psoriasis inversa: pliegues

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Psoriasis: patrones clinicos

A
  • psoriasis en placa (80-90%)
  • psoriasis gutatta (2%) (>niños) (infx o corticoides)
  • psoriasis pustular (infrecuente): localizada (palmoplantar) o generalizada (infx, embarazo, suspension corticoides)
  • psoriasis eritrodermica -> urgencia dermatologica
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

comorbilidades asociadas: psoriasis

A
  • sd metabolico
  • eii
  • enf CV
  • artritis psoriatica
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Psoriasis: clasificacion severidad

A

segun BSA
leve: <10%
mod: 10-20%
severa: >20%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Psoriasis: diagnóstico

A

clinico

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Psoriasis: manejo

A

1) educacion
2) medidas no farmacologicas: baños cortos, evitar traumas, humectar (con urea)
3) medidas farmacologicas: 1º linea corticoesteroides x 3meses

<10% bsa: topica
>10% bsa: sistemica –> derivar

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Psoriasis: criterios de derivacion 4

A
  • duda diagnóstico
  • bsa >10% (moderada en adelante)-
  • refractario
  • artritis psoriatica : reumato
How well did you know this?
1
Not at all
2
3
4
5
Perfectly