Psoriasis

Question 1

Define psoriasis.

Answer 1

Psoriasis is a chronic inflammatory skin disease characterised by erythematous, circumscribed scaly papules, and plaques. It can cause itching, irritation, burning, and stinging.

Question 2

Explain the aetiology/risk factors of psoriasis.

Answer 2

Genetic
Infection
Local trauma

Question 3

Summarise the epidemiology of psoriasis.

Answer 3

In most developed countries, prevalence is between 1.5% and 5.0%; there is some evidence that prevalence is increasing in these regions. The mean age of onset is 28 years, with equal distribution between men and women.

Question 4

Recognise the presenting symptoms of psoriasis. Recognise the signs of psoriasis on physical examination.

Answer 4

Skin lesions
Skin discomfort
Plaques

Psoriatic lesions are red, inflamed, silvery-white scaly, and circumscribed papules and plaques; often affecting elbows, knees, extensor limbs, and scalp, and, less commonly, nails, ear, and umbilical region.

Question 5

Identify appropriate investigations for psoriasis and interpret the results.

Answer 5

Usually no tests are necessary.

Question 6

What is the management for psoriasis?

Answer 6

Topical hydrocortisone, Topical fluocinonide
Methotrexate
Oral retinoid
Ciclosporin

Question 7

What are complications associated with psoriasis?

Answer 7

Cardiovascular complications

Psoriatic arthritis

Depression

Lymphoma

Secondary infection

Question 8

What is the prognosis for psoriasis?

Answer 8

The exact natural history of psoriasis is poorly understood. However, psoriasis is generally considered a chronic disease with a fluctuating course. Long-term control with topical and/or systemic medications is necessary for many patients.