Pseudomonas

Question 1

What is th emetabolism of Psuedimonas?

Answer 1

Oxidase-Positive, Obligate Aerobe

can use nitrite for respiration

Question 2

Where would you like to find psuedomonas?

Answer 2

it likes water and plant material

Question 3

What type of pigment does psuedomonas produce?

Answer 3

green pigment
green pus

produce a grape like aroma

Question 4

Which species of psuedomonas cause the most infection?

Answer 4

aeruginosa

Question 5

is psuedomonas oppurtunistic?

Answer 5

yes, it is an oppurtunistic pathogen
very antibiotic resistant

people with cystic fibrosis are very susceptible and burns

Question 6

What are the virulence factors of psuedomonas?

Answer 6

1. Pili:
2. Polysaccharide capsule
3. Exotoxin A:
4. Exoenzyme S:
5. Cytotoxin:
6. Extracellular proteases: (proteases and hemolysisns)
7. Phospholipase:
8. Endotoxin:

Question 7

What is the function of Exotoxin A?

Answer 7

close to diphtheria toxin

irreversibly blocking protein synthesis

Question 8

What is exoenzyme S

Answer 8

an effector protein that is injected into cells by a Type III secretion system encoded on the chromosome of Pseudomonas aeruginosa. Its target protein is a small G protein (Ras), and ADP ribosylation of this protein results in collapse of the cytoskeleton.

Question 9

what are the extracellular proteae?

Answer 9

LasB elastase
LasA eleastase
alkaline elastase

breaks down connective tissue

Question 10

What are the hemolysisn?

Answer 10

phospholipase C
Rhamnolipid

breaks down phospholipids