Pseudoexfoliation Syndrome Flashcards
Describe pseudoexfoliation syndrome:
Build up of white flaky dandruff like material which clogs up the trab and prevents outflow of aqueous which leads to an increase of iop
Who is pseudoexfoliation most common in?
In older px’s and increases with age
Who is pseudoexfoliation rare in?
Px’s younger than 50
What is the prevalence of pseudoexfoliation in 55-65 yrs?
0.80%
What is the prevalence of pseudoexfoliation in over 85s?
6.25%
Which gender is more at risk of pseudoexfoliation?
Women
Which ethnicity is pseudoexfoliation more common in?
Scandinavian and Greek px’s
Is pseudoexfoliation unilateral or bilateral?
Unilateral but the fellow eye will follow over time
What is pseudoexfoliation caused by?
Abnormal and excessive production of extra cellular material. The fibrous material is then deposited on several structures including the lens capsule, lens zonules, iris and trab and the increase of material in the trab leads to inhibition of aqueous drainage leading to an increase of iop
What does a rise in iop cause?
Onh and ganglion cell death damage
In pseudoexfoliation what will the anterior lens demonstrate?
A bullseye pattern which is a central and outer disc separated by a clear band
What is the clear band in pseudoexfoliation caused by?
By the movement of the iris across the mid zone of the lens during mydriasis and miosis
What does the central disc in pseudoexfoliation appear like?
White and granular appearance and dine feathery threads of material may form in the periphery
Why is dilation needed for pseudoexfoliation?
To ensure there’s no peripheral pseudoexfoliation in the periphery (fine feathery threads)
Does having pseudoexfoliation mean glaucoma is present?
No
What is the prevalence of px’s that have pseudoexfoliation who show signs of glaucoma?
Less than 1/3
What is the risk of developing glaucoma 5 years after the detection of pseudo?
50%
If the optom suspects that pseudo is present, what do they need to do?
they need to carry out full assessments of glaucoma for example fields, iop and DISC assessment)
What is more aggressive, pseudo or POAG?
Pseudo
what are px’s with pseudo at risk of?
Substantial glauc damage and increased iop and spikes in iop
What is needed to be monitored in px’s with pseudo?
Anterior chamber depth with gonioscopy
What is the referral for px’s with pseudo?
Refer routine regardless of whether there’s glauc damage or not
