PSA mocks Flashcards

(78 cards)

1
Q

what is the first line treatment of DVT or PE

A

apixaban or rivaroxaban

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2
Q

what is an appropriate infusion rate for maintenance fluids?

A

500ml over 4-6hrs
or
1L over 8-12hrs

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3
Q

what is the anticipated daily potassium requirement per day?

A

1mmol/kg/day

Hartmanns doesnt have enough K in for some pts. it should be NaCl 0.9% + Kcl 0.3%

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4
Q

starting dose for primary prevention of CV events statins are ……

A

20mg atorvastatin

as opposed to 10mg for cholesterol lowering

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5
Q

what time of day should you take statins?

A

night

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6
Q

ibuprofen and ACEis

A

less renal blood flow - renal impairment

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7
Q

does pioglitazone cause hypos?

A

yes.

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8
Q

does metformin cause hypos?

A

NO.

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9
Q

name 3 drugs that can cause urinary retention

A

anticholinergics
benzos
opioids!

but also: CCBs, antihistamines

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10
Q

if you’re getting confused about whether a drug causes confusion, think about whethers its site of action is in:

A

the CNS

e.g. metoclopramide, morphine, antidepressants, anticonvulsants, antipsychotics.

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11
Q

what is the triad of wernickes encephalopathy?

A

opthalmoplegia, ataxia and confusion

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12
Q

as well as IV sodium chloride, what is the treatment for DKA?

A

fixed rate insulin infusion 0.1 units/kg/hr

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13
Q

what dose of folic acid for a pregnant woman at HIGH risk of conceiving a child w neural tube defects?

A

5mg daily

for low risk 400mcg

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14
Q

should take folic acid until which wk of preg

A

peri-conception to wk 12

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15
Q

can gliclazide cause hypos?

A

yes - its a suphonylurea

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16
Q

does HRT increase risk of breast cancer?

A

yes.

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17
Q

what does a 0.1%solution mean?

A

it means 0.1g per 100ml

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18
Q

what is a 100% solution

A

100g per 100ml

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19
Q

what is a 50% solution

A

50g per 100ml

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20
Q

a 0.1% solution is contains how many mg

A

0.1% solution = 0.1g per 100ml

= 100mg per 100ml

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21
Q

common SE of methotrexate which needs monitoring w FBC?

A

leucopenia

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22
Q

how does gentamicin cause ototoxicity?

A

damages vestibular nerve

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23
Q

why does clarithromycin interact w simvastatin to muscles aching

A

its a CYP450 inhibitor

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24
Q

which blood test is good for monitoring the beneficial effects of allopurinol rx

A

serum urate

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25
what kind of drug is allopurinol
xanthine oxidase inhibitor
26
best measure of fluid replacement in early stages
BP
27
two renal adverse effects of lithium
nephrotic syndrome | nephrogenic diabetes insipidus
28
when starting HRT what should you monitor?
BP (can raise it)
29
how raised do your transaminases have to be to stop statins?
3 times the upper limit test transaminases before rx, at 3 months and 12 months
30
pulmonary oedema which requires immediate treatment. what is the IV furosemide dose range?
IV furosemide 20-50mg
31
what is the alternative to dalteparin (LMWH) for thromboprophylaxis?
rivaroxaban | remember, the dose of dalteparin is higher if theyre high risk
32
give two other LMWH as well as dalteparin
tinzaparin | enoxaparin
33
what is the first line IV treatment of hypoglycaemia?
glucose 20% 100ml over 20 mins
34
why don't you use IV glucose 50% in treatment of hypoglycaemia ?
hypertonic - risks extravasation
35
why don't you use IV glucose 5% in treatment of hypoglycaemia?
too weak - too large a volume would be required
36
how many grams in 10% solution
10% solution = 10g in 100ml
37
how many grams in 1% solution
1% solution = 1g in 100ml
38
how any grams in 20% solution
20% solution = 20g in 100ml
39
what has lymecylcine taught you
READ THE RIGHT DOSE FOR THE RIGHT INDICATION
40
apart from lymecycline for acne, what are some other abx choices?
oxytetracycline doxycycline tetracycline erythromycin
41
is aspirin stopped before surgery?
yes - antiplts should be stopped up to 7 days before surgery
42
why withold allopurinol in renal dysfunction?
can accumulate
43
do steroids contribute to hyperglycaemia?
yes
44
can steroids cause confusion?
yes
45
if looking for serious prescriptions errors where shouldn't you forget to look
frequency column - e.g. might say weekly when its supposed to be daily
46
can you use fentanyl nasal spray for breakthrough pain?
yes
47
nitrofurantoin should be avoided when...?
eGFR <45 can use short course trimethoprim even if folate def
48
what do you give if INR >1.5 the day before surgery?
oral vit K | reverse the last bit of warfarin to stop bleeding
49
what do you have to watch out in the first 4 wks of starting sertraline?
suicidal ideation may worsen
50
should rivaroxaban be taken w food?
yes
51
how many nanograms in a microgram?
1000
52
which antibiotic commonly causes jaundice?
co-amoxiclav
53
what do you do if there is a small rise in serum creatinine on starting an ACE inhibitor
normal. don't need to change drug. repeat U&Es after 1 wk.
54
what parameter indicates effective treatment of oedema w furosemide?
weight
55
what is a serious adverse effect of carbimazole?
neutropenia - monitor FBC (WCC) - watch out for sore throat
56
what are the most serious adverse effects of ciclosporin?
nephrotoxicity and hypertension check U&Es @baseline and every 2 wks until stable!
57
whats the most appropriate way to manage a transient rise in blood glucose caused by corticosteroids?
a 10% increase in the usual dose
58
which anti emetic DOESNT prolong QT
cyclizine (antihistamine)
59
whats the usual antiemetic for post op nausea and vomiting
ondansetron
60
vomitnig for 3 days, needs fluid resuscitation?
hartmanns 500ml bolus over 15 mins
61
what is the treatment of croup?
dexamethasone 0.15mg/kg
62
can naproxen cause ankle swelling?
yes
63
are beta blockers bad in peripheral vascular disease?
yes
64
what is the treatment for scarlet fever?
pen V (phenoxymethylpenicillin)
65
Pen G is what?
benpen
66
gemifobrozil + simva =
mytoxicity
67
CK above 5 times upper limit?
stop statin then reintroduce at lower dose
68
do u need longer treatment for thrush in pregnancy?
yes
69
first line therapy for C.diff infections?
metronidazole
70
recurrent C.diff therapy?
vancomycin (metronidazole has failed or not tolerated)
71
pt in DKA. should you continue their long acting insulin while theyre on fixed rate insulin infusion?
yeh | stop short acting
72
simplest initial approach to acute pain in personal who might be vulnerable to SEs of nsaids or opiates
paracetamol
73
when should loperamide be taken
after each loose stool
74
can tramadol help precipitate serotonin syndrome?
yar!
75
when should you stop a COCP according to BP
if BP >160/90 (tips into cat 4)
76
if on apixaban report what immediately
bleeding and bruising
77
which form of opiate accumulates less in renal impairment?
oxycodone cos of the way its metabolised
78
someone has thyrotoxicosis with amiodarone. do what?
withdraw temporarily to achieve control