PSA - Drug Information Giving

Question 1

Tamoxifen (Oestrogen sensitive Hormone therapy) Breast cancer

• oestrogen rec, blocker on breast cells

Side effects:
Increase… (3)
Side effect (1)

Answer 1

• increases endometrial cancer risk
• increase VTE risk
• increases Warfarin efficacy
• Hot flushes

Question 2

Gliclizide (sulfonylurea)
- main side effect/ risk?

When should it be taken?

Answer 2

1. Hypoglycaemia

In the morning with breakfast
If daily dose >160mg give divided doses but at meal times

Question 3

Warfarin dose and colour of tablet

0.5 mg =
1mg =
3mg =
5mg =

Answer 3

0.5 mg = white
1mg = Brown
3mg = blue
5mg = pink

Question 4

Starting ramapril in elderly, what do they need to be carful about?

When do you measure U&Es after commencing to check renal function impact?

Answer 4

Diarrhoea and vomiting as can cause AKI

1-2 weeks after?

Question 5

S
T
E
R
O
I
D
S

Answer 5

S - stomach ulcer
T thin skin
E - oEdema
R - right and left HF
O osteroperosis
I infection risk inc
D diabetes (hyperglycaemia)
S - syndrome Cushings

Question 6

HRT

Combined - does it have more of an increase in breast cancer than oestrogen only?

How many years after stopping HRT does risk of breast cancer still occur?

Is breast cancer risk attributed to age of starting HRT or duration?

Answer 6

Yes

10 years

Duration of use