PSA Flashcards

1
Q

Mx of STEMI

A
ABC + resus + O2
Aspirin 300mg PO
Morphine 5mg IV + metoclop 10mg IV
GTN spray
Primary PCI or thrombolysis (+ repeat ECG)
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2
Q

Mx of NSTEMI

A
ABC + resus + O2
Morphine 5mg IV + metoclop 10mg IV
GTN spray
Aspirin 300mg PO 
LMWH!!! 1mg/kg SC
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3
Q

Mx of acute pulmonary oedema

A
ABC + resus + 02
Sit up
Morphine 5mg IV  metoclop 10mg IV
Furosemide 40mg IV
If failing --> Isosorbide dinitrate infusion + CPAP
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4
Q

Mx of tachycardia + shock/MI/syncope/LVF

A

synchronised DC shock 3x
Amiodarone 300mg IV over 10-20 mins

Repeat amiodarone 900mg over 24 hours

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5
Q

Mx of a regular, narrow complex tachycardia?

A

Vagal manœuvres
Adenosine 6mg IV rapid bolus!
Repeat with 12mg. Repeat with 12mg

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6
Q

Mx of regular, broad complex tachycardia

A

Amiodarone 300mg IV over 20 mins

Then, amiodarone 900mg IV over 24 hours

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7
Q

Pt on warfarin w major bleed - what do you do?

A
  • STOP warfarin
  • Vitamin K 5-10mg IV
  • Prothrombin complex
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8
Q

Pt on warfarin w INR 7

A

Omit warfarin for 2 DAYS

Then, reduce dose

if minor bleed –> also give oral vitamin K

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9
Q

Pt on warfarin w INR 9

A

Omit warfarin

Vitamin K 1-5mg oral (even if there’s no bleed)

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10
Q

If a pt is stable w acute exacerbation of COPD, how much oxygen should be given?

A

28% O2 (roughly 2L) –> check ABG 30 mins later

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11
Q

Mx of anaphylaxis

A

Adrenaline IM 500micrograms
Chlorphenamine IV 10mg
Hydrocortisone IV 200mg

If wheeze - salbutamol nebs

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12
Q

CURB 65?

A

Confusion (AMTS 8)
Urea (>7.5)
RR (>30)
BP (<90)

> 65yo

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13
Q

Pulmonary embolism: how is LMWH given?

A

Tinzaparin

175 units/kg SC OD

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14
Q

In a GI bleed, if PT or APTT is >1.5x thermal range, what must you give?

A

FFP

UNLESS the bleed is due to warfarin, in which case give prothrombin complex

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15
Q

Mx of acute GI bleed

A

O2
Fluid resus - 0.9% saline 500mL bolus
Catheter to monitor UO
Bloods: clotting, G+S, X-Match 6 units, FBC, LFTs, U+Es

Correct clotting: if prolonged PT/APTT –> FFP
Urgent OGD
Call surgeons

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16
Q

immediate medication given for suspected bacterial meningitis

A

IM benpen
IV fluids
IV dexamethasone 10mg

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17
Q

Mx of status

A

Airway - patent?
Recovery position
O2
Bloods: look for precipitating factors (infection, electrolytes, glucose, drugs)

If lasting >5 mins:
-IV LORAZepam/buccal MIDAZolam/IV DIAZepam

  • Repeat diazepam after 2 mins
  • Inform anaesthetics + ITU + consider phenytoin
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18
Q

Timelimit for thrombolysis in acute ischemic stroke

A

<4.5hours

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19
Q

Mx of DKA

A

Airway - patent
Breathing - O2? ABG? order CXR?

Circulation:

  • Bloods: FBC, U+Es, ketones, glucose, CRP
    1) SBP<90 –> 0.9% saline 500mL bolus
    2) Fluids: 0.9% saline 1L over 1 hour, then over 2 hrs, 4 hrs, 8hrs
    3) Insulin: 1 unit/1mL of saline. 0.1 units/kg/hr.
    4) Replace K if <5.5 –> 40mM of K/1L of saline

Aim for ketones to reduce by 0.5mM/L/hr

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20
Q

Diagnosis of HONK?

Mx of HONK

A

Glucose >35
Osmolality >340
No ketones

Similar to DKA but half the rate of fluid infusion (500mL over 1 hour, then 2 hours, then 4 hours etc)
+ insulin + K replacement

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21
Q

Mx of hypoglycemia

A

Eat food
IV glucose 100mL of 20%
Im glucagon 1g

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22
Q

target BP in <80yo?

>80yo?

A

<80yo: <135/85 at home (140/85 in clinic)

> 80yo: 145/85 at home (150/85 in clinic)

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23
Q

Atrial fibrillation:

in whom would u consider rhythm control?

A

New onset AF + Haemodynamically unstable –> Electrical cardioversion

Stable + onset <48 hours –> rate or rhythm control (amiodarone 5mg/kg IV)

Stable + onset >48 hours or uncertain –> rate control + anticoagulation for 3 weeks, delay rhythm control

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24
Q

Mx of new onset AF (24 hours ago):

A

Rate control or rhythm control w

Amiodarone IV 5mg/kg

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25
Rate control in AF?
Propanolol 10mg/6hrs or Diltiazem 120mg/day
26
Mx of stable angina
- GTN spray PRN - Aspirin - Statin - CVS RF control - one anti-angina drug: beta blocker(asthma!) or CCB (oedema!)
27
Mx of stable angina in a pt who cannot tolerate B-blockers or CCBs?
GTN spray PRN Aspirin Statin CVS RF modification Long acting nitrate( isosorbide mononitrate) or K channel activator (nicorandil)
28
What test is done to check for nephropathy in DM?
Albumin:creatinine ratio
29
eg of long-acting insulin
GLargine
30
Indication for oral hypoglycemics in T2DM
HbA1c =>48mM/L (after diet + exercise)
31
1st line medical mx of T2DM
Metformin 500mg w breakfast
32
1st line medical mx of T2DM - when might you NOT use metformin?
If pt is low/normal weight, or if their creatinine>150 Gliclazide!
33
T2DM: if pt is still HbA1c>48 and on metformin + gliclazide... what can you give?
Gliptin (DPP-4 inhibitor)
34
mediations to avoid in PD patients?
Haloperidol + metoclopramide
35
Commonly used drug in PD
Co-beneldopa | or co-careldopa
36
2 drugs used for absence seizure mx?
VPA | ethosuximide
37
2 drugs used for focal seizure mx? side effects?
VPA - teratogenicity | Lamotrigine - rash
38
Crohns disease: what drugs are used to treat a flare up?
Mild: oral pred | Moderate/severe: IV hydrocortisone 100mg/6hrly + supportive Mx
39
Crohns disease: what drugs are used to maintain remission? cautions?
Azathioprine or 6 mercaptopurine MUST check TPMT activity before starting: if low, there is risk of toxicity. consider MTX in those patients
40
Maintenance treatment of Rheumatoid arthritis
Methotrexate + another DMARD: sulfasalazine or hydroxychloroquine ^if poor response to 2 DMARDs --> add anti-TNF
41
Mx of a flare in RA?
Short term steroids: IM methylpred Short term NSAIDs: ibuprofen + PPI Reinstate DMARDs if dose was recently reduced
42
indications for 5% dextrose (and not NS) in fluid management?
Hypoglycaemic or hypernatremic
43
Fluid replacement in pt with ascites? why?
Human Albumin Solution (HAS) - maintains oncotic pressure
44
General rule for maintenance fluid in adults?
3L a day: 1L of 0.9% saline 2L of 5% dextrose Add K (guided by U+Es) - approx 40mM/day
45
Pain relief: for mild pain - regular vs PRN?
Regular: Paracetamol 1g every 6 hours PRN: Codeine 30mg - max every 6 hours
46
Pain relief for severe pain - regular vs PRN?
Regular: Co-codamol 30/500, 2 tablets every 6 hours PRN: Morphine sulphate 10mg, max every 6 hours
47
Anti-emetics: which are best to use?
Cyclizine UNLESS they have heart failure --> give metoclopramide
48
Mx of painful diabetic neuropathy
Duloxetine
49
Stimulant laxative? -ve effect?
Senna | Can worsen abdo cramps
50
Osmotic laxative? -ve effect?
Phosphate enema or Lactulose | Can worsen bloating
51
Bulking laxative? -ve aspect?
Isphagula husk - but takes days to take effect
52
Stool softener laxative?
Docusate
53
Mx of chronic diarrhoea
``` Loperamide - 2mg, max every 3 hours or codeine (if painful) - 30mg every 6 hours ```
54
Pts with insomnia: what must you consider first? Appropriate medication?
Are they on corticosteroids? Consider zopiclone 7.5mg (or 3.75 if elderly!)
55
Which medication which is used for neuropathic pain, can causeneutropenia?
Carbemazepine
56
Drugs with antimuscarinic side effects: Anti-emetic? Neuropathic pain relief?
cyclizine | amitriptyline
57
Which 2 drugs are defo best avoided in parkinnsons?
Haloperidol | Metoclopramide
58
What does 1% lidocaine actually mean
1g of lidocaine in 100mL
59
General threshold for RBC transfusion
Hb<70g/L OR <80g/L in ACS
60
When NOT to give platelets prophylactically?
ITP TTP Heparin induced thrombocytopenia Chronic BM failure
61
Indications for FFP?
if APTT or PT are prolonged + pt is bleeding/due surgery
62
Indication for cryoprecipitate
Low fibrinogen AND bleeding/due surgery