PSA Flashcards
Drugs which increase risk of falls
- benzos
- antidepressants
- MAOI
- most antipsychotic s
- opiates
- anti-hypertensives (particualrly diuretics and alpha-blockers)
Drugs which increase the risk of fractures
PPI
steroids
GnRH agonists (buserelin, goserelin)
Which two T2DM medications can result in pancreatits
- DDP4i (sitagliptin) and GLP1 analogue (exenatide)
THiazolidinedione SE
oedema
HF
post menopausal OP
bladder cancer
weight gain
DDP4i SE
pancreatitis
nasopharyngitis
a-glucodiase inhibitor (acarbose) SE
bloating
flatulence
diarrhoea
GLP1 analogue SE
-nausea
-diarrhoea
- pancreatitis
which diabetic medication can result in weight gain
sulphonureas, thiazolidinedione, insulin
Drugs to stop in AKI
Stop the DAMN drugs
diuretics
acei/arb
metformin
nsaids
Lithium - excretion reduced by
ACEi, thiazides, NSAIDS
Liver injury and drugs - ALT : ALP 2-5
mixed picture
Phenytoin
Sulphonamides
Carbamazepine
Liver injury and drugs - ALT : ALP <2
cholestatic picture
Co-amoxiclav
Erythromycin
Chlorpromazine
Hormonal contraceptio
Liver injury and drugs - ALT : ALP >5
hepatocellular picture
Paracetamol
NSAIDs
Statins
Amiodarone
NSAID SE
Stomach ulcers
ARF
Bronchoconstriction - asthma
Peripheral oedema
Thiazide SE
Hypokalaemia, dyslipidaemia (inhibits lipoprotein lipase), gout, hyponatraemia, hypercalcaemia
when is the best time to take drugs
steroids - morning
bet blockers - morning
diuretics - morning
anti-hypertensives - evening
Beta blocker SE
bronchoconstriction
bradycardia
interaction with levothyroxine
iron and calcium
leave at least a 4 hour gap
how is moderate UC defined
In a mild-moderate flare of ulcerative colitis extending past the left-sided colon, oral aminosalicylates should be added to rectal aminosalicylates, as enemas only reach so far
monitoring for anticoagulants
LMWH – anti-factor Xa
Unfractioned heparin – aPTT
NOACs – monitor clinically
Warfarin – INR
best anti emetic for Parkinsons
domperidone
most likely to cause hyperglycaemia
steroids
antipsychotics
thiazides
beta blockers
tacrolimus
most likely to cause diarrhoea
antibiotics
colchine
metformin
PPI
antacids that contain magnesium
laxative
most likely to cause urine incontinence
alpha-blockers
diuretics
anticholinesterase inhibitors
cloazapine
most likely to cause high cholesterol
steroids
thiazides
most likely to cause hypertension
NSAID
steroid
oral contraception
mirabegron
causes of hypokalaemia
loop diuretics
thaizides
steroids
salbutamol
cause of hyperkalaemia
K+ sparing diuretics
ACEi
ARBs
unfractionated or LWMH
blood transfusion
cause of hyponatraemia
SSRI
TCA
carbamazepine
opiates
PPI
most likely to worsen myasthenia gravis
antibiotics
beta blockers
local anaethetic
sedating drugs
