PSA Flashcards

1
Q

Drugs which increase risk of falls

A
  • benzos
  • antidepressants
  • MAOI
  • most antipsychotic s
  • opiates
  • anti-hypertensives (particualrly diuretics and alpha-blockers)
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2
Q

Drugs which increase the risk of fractures

A

PPI
steroids
GnRH agonists (buserelin, goserelin)

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3
Q

Which two T2DM medications can result in pancreatits

A
  • DDP4i (sitagliptin) and GLP1 analogue (exenatide)
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4
Q

THiazolidinedione SE

A

oedema
HF
post menopausal OP
bladder cancer
weight gain

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4
Q

DDP4i SE

A

pancreatitis
nasopharyngitis

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5
Q

a-glucodiase inhibitor (acarbose) SE

A

bloating
flatulence
diarrhoea

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6
Q

GLP1 analogue SE

A

-nausea
-diarrhoea
- pancreatitis

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7
Q

which diabetic medication can result in weight gain

A

sulphonureas, thiazolidinedione, insulin

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8
Q

Drugs to stop in AKI

A

Stop the DAMN drugs

diuretics
acei/arb
metformin
nsaids

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9
Q

Lithium - excretion reduced by

A

ACEi, thiazides, NSAIDS

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10
Q

Liver injury and drugs - ALT : ALP 2-5

A

mixed picture
Phenytoin
Sulphonamides
Carbamazepine

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11
Q

Liver injury and drugs - ALT : ALP <2

A

cholestatic picture
Co-amoxiclav
Erythromycin
Chlorpromazine
Hormonal contraceptio

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12
Q

Liver injury and drugs - ALT : ALP >5

A

hepatocellular picture
Paracetamol
NSAIDs
Statins
Amiodarone

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13
Q

NSAID SE

A

Stomach ulcers
ARF
Bronchoconstriction - asthma
Peripheral oedema

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14
Q

Thiazide SE

A

Hypokalaemia, dyslipidaemia (inhibits lipoprotein lipase), gout, hyponatraemia, hypercalcaemia

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15
Q

when is the best time to take drugs

A

steroids - morning
bet blockers - morning
diuretics - morning

anti-hypertensives - evening

16
Q

Beta blocker SE

A

bronchoconstriction
bradycardia

17
Q

interaction with levothyroxine

A

iron and calcium

leave at least a 4 hour gap

18
Q

how is moderate UC defined

A

In a mild-moderate flare of ulcerative colitis extending past the left-sided colon, oral aminosalicylates should be added to rectal aminosalicylates, as enemas only reach so far

19
Q

monitoring for anticoagulants

A

LMWH – anti-factor Xa
Unfractioned heparin – aPTT
NOACs – monitor clinically
Warfarin – INR

20
Q

best anti emetic for Parkinsons

A

domperidone

21
Q

most likely to cause hyperglycaemia

A

steroids
antipsychotics
thiazides
beta blockers
tacrolimus

22
Q

most likely to cause diarrhoea

A

antibiotics
colchine
metformin
PPI
antacids that contain magnesium
laxative

23
Q

most likely to cause urine incontinence

A

alpha-blockers
diuretics
anticholinesterase inhibitors
cloazapine

24
Q

most likely to cause high cholesterol

A

steroids
thiazides

25
Q

most likely to cause hypertension

A

NSAID
steroid
oral contraception
mirabegron

26
Q

causes of hypokalaemia

A

loop diuretics
thaizides
steroids
salbutamol

27
Q

cause of hyperkalaemia

A

K+ sparing diuretics
ACEi
ARBs
unfractionated or LWMH
blood transfusion

28
Q

cause of hyponatraemia

A

SSRI
TCA
carbamazepine
opiates
PPI

29
Q

most likely to worsen myasthenia gravis

A

antibiotics
beta blockers
local anaethetic
sedating drugs