Provocative tests: syncope and tilt testing Flashcards

1
Q

Causes of syncope

A

-Arrhythmic
-Metabolic
-Neurogenic
-Psychogenic
-Respiratory
-Trauma

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2
Q

Why do you pass out from tachyarrhythmia?

A

-Decreased filling time (shorter diastole)
-Decreased emptying (shorter systole)

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3
Q

Transient loss of consciousness definition?

A

A state of real or apparent loss of consciousness with:
-loss of awareness, characterised by amnesia for the period of unconsciousness
-abnormal motor control
-loss of responsiveness
-a short duration

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4
Q

Syncope definition

A

Transient loss of consciousness due to cerebral hypoperfusion characterised by:
-a rapid onset
-short duration
-spontaneous complete recovery

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5
Q

Causes of syncope

A

Main cause is reflexes:
-Vasovagal
-Situational syncope
-Carotid sinus syndrome
-Orthostatic hypotension (OH)
-Cardiac syncope

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6
Q

Assessments for syncope?

A

Vital signs:
-Lying and standing blood pressure
-Blood glucose level
-Cardiac and neurological examination

-12 lead ECG
-blood test
-24 hr blood pressure/ecg
-echo

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7
Q

Questions to ask patient/first hand witness after syncope?

A

-Posture beforehand?
-Prodromal symptoms?
-Tongue biting?
-Loss of bladder/bowel control?
-Confusion afterwards?
-Family history of cardiac disease/SCD?

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8
Q

What warrants specialist referral? (syncope clinic/cardiologist)

A

-Diagnostic uncertainty
-Unexplained syncope
-Vasovagal syncope during high risk activity/affecting QoL
-Reflex syncope with absent/short prodrome
-Suspected but unconfirmed orthostatic hypotension
-Persistent orthostatic hypotension despite lifestyle modification

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9
Q

NICE guidelines for syncope

A

-Examination
-History
-12 lead ECG
-Blood tests
-24hr BP monitor
-Echo
-Video of event

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10
Q

Indications for Tilt test

A

-Clinical history suggestive of vasovagal syncope/reflex syncope
-Orthostatic intolerance
-Suspected autonomic dysfunction
-Risk stratification

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11
Q

Contraindications to Tilt test

A

Absolute:
-Inability to stand/weight bear

Relative:
-Recent stroke
-Airway support
-History of catastrophic tachyarrhythmia
-Aortic/mainstem stenosis

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12
Q

Clinical questions in Tilt testing

A

-Can syncope be reproduced by Tilt testing?
-Are symptoms reproduced in study consistent with clinical history?
-What were the haemodynamic findings?

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13
Q

Clinical history of Tilt testing

A

3 P’s
-posture
-prodrome
-provocational factors

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14
Q

Prodromes in Tilt testing

A

-Nausea/vomiting
-Diaphoresis/skin tone
-Altered vision/hearing
-Incontinence
-Witness observations
-Chest pain
-Palpitations

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15
Q

Provocational factors of syncope

A

-Exercise - during or immediately after
-Eating/alcohol consumption
-Crowded room/hot environment
-Public speaking/situational
-Micturition
-Coughing
-Menstruation

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16
Q

What monitoring should all Tilt tests have?

A

-Continuous measurement of heart rate and blood pressure

17
Q

What is the Italian protocol?

A

-5 minutes supine
-20 minutes passive tilt at 60-70 degrees
-400mcg of GTN
-Further 15 minutes of Tilt

18
Q

Non-provocational testing

A

-5 minutes supine
-45 minutes tilt at 60-70 degrees

19
Q

What are the outcomes of a Tilt test?

A

-Negative/normal test
-Syncope/presyncope with vasovagal response
-Syncope/presyncope with orthostatic hypotension response
-Symptoms reproduced with haemodynamic features of postural orthostatic tachycardia syndrome (POTS)

20
Q

How does GTN affect heart rate?

A

-Increases HR
-Contraindicated in asthma patients

21
Q

What Tilt test is this?

A

-Orthostatic hypotension
-HR goes up
-BP goes down

22
Q

What Tilt test is this?

A

Vasovagal

23
Q

What Tilt test is this?

A

POTS
-Heart rate rapidly increases

24
Q

What is included in Tilt report?

A

Haemodynamic trends:
-maximum/minimum values
-correlation with reported symptoms

Symptoms reproduced
-Consistent with clinical history?