Protozoa & Disease Flashcards

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1
Q

Potozoa cell morphology

A
  • Nucleus (eukaryotic)
  • Flagellum
  • Cilia
  • Golgi
  • Endoplasmic reticulum
  • Mitochondrion
  • Plasma membrane
  • Apicoplast (similar to chloroplast)
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2
Q

How do protozoa reproduce

A
  • All reproduce asexually (budding, mitosis)
  • Not all reproduce sexually
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3
Q

What kind of mosquitoes cause malaria

A

Female Anopheles mosquito

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4
Q

5 species of plasmodium (causative organisms of malaria)

A
  • P. falciparum (most deadly)
  • P.vivax (most common)
  • P. ovale
  • P. malariae
  • P. knowlesi
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5
Q

Where are merozoites formed in malaria transmission

A

In liver cells

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6
Q

Steps in malaria transmission

A
  • Infected by mosquito bite
  • Merozoites formed in liver cells
  • Merozoites released & rbcs infected
  • Rings form in rbcs
  • Asexual reproduction occurs to form trophozoites and then schizont
  • Gametocytes are formed which are taken back up by mosquitoes for sexual reproduction between mozzies
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7
Q

Symptoms of malaria (8)

A
  1. Anaemia
  2. Splenomegaly (enlargement of the spleen)
  3. Fever
  4. Nausea
  5. Vomiting
  6. Rigors (sudden feeling of cold with shivering accompanied by a rise in temp)
  7. Headache
  8. Coma
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8
Q

Which malaria plasmodium causes severe symptoms and sometimes cerebral malaria

A

P. falciparum

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9
Q

What makes you attractive to mosquitoes

A
  1. Body odour: certain compounds in breath, skin, sweat attract
  2. Skin bacteria: high diversity of microbes on skin will repel
  3. Pregnancy: more attractive due to body temp increase
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10
Q

What is Chagas Disease caused by

A

Protozoa spread by:
Reduviid bug
Kissing bug
Vampire bug

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11
Q

What is Babesiosis caused by

A

Babesia microti
A protozoan transmitted by deer tick

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12
Q

Some symptoms of Babesiosis

A

Fever
Haemolytic anaemia
(Caused by infection of rbcs)

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13
Q

What do P. falciparum & Babesia microti look like on a blood film

A

Maltese cross

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14
Q

Babesiosis: at risk groups

A
  1. Splenectomised (surgical removal of spleen)
  2. Immunocompromised
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15
Q

What is the transmission of Cryptosporidium spp. associated with

A

Untreated water & swimming pools

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16
Q

Cryptosporidium infection cycle

A
  • Humans ingest thick walled oocyst in contaminated water
  • Parasites reproduce in small intestine (humans are the intermediate host)
  • Oocyst released into envrionment
  • Water and food from human populated areas get contaminated with oocysts