protozoa Flashcards
protozoa features
unicellular, eukaryotic, many are mobile
amebas
move by extending cytoplasmic projections
flagellates
move by rotating whip like flagellates
sporozoan
non motile adult forms
intestinal parasites
Entamoeba histolytica (ameba), Giardia lamblia (flagellate), Cryptosporidium parvum (sporozoan)
urogenital parasites
Trichomonas vaginalis (flagellate)
blood and tissues parasites
Plasmodium species (sporozoan), Toxoplasma gondii (sporozoan), Trypanosoma species (flagellate), Leishmania species (flagellate), Acanthamoeba castellanii (ameba)
Enantamoeba histolytica
ameba, intestinal; infects colon with secondary infection of liver; dx by presence of characteristic cysts in stools (infectious cysts)
Giardia lamblia
flagellate, intestinal; infection results from drinking contaminated water; incubation of 10days; acute infection sudden onset with foul smelling diarrhea; dx by presence of cysts or trophozoites in stools; most commonly diagnosed parasitic INTESTINAL infection in US
Cryptosporidium parvum
sporozoan, intestinal; infects lower small intestine; organisms are INTRACELLULAR parasites; dx by modified acid fast stain of stool sample
Trichomonas vaginalis
flagellate, urogenital; infects vagina, vulva, and cervix in females; infects urethra, prostate and seminal vesicles in males; higher than normal pH favors disease (common UTI)
Trypanosoma brucii
flagellate, blood and tissues; African sleeping sickness; vector is tsetse fly; primary lesion (chancre); spreads to lymph and then CNS
Plasmodium species
sporozoan, blood and tissues; malaria–acute infectious disease of the blood (mosquito is vector), asexual repro in human cells, sexual repro in mosquito; dx depends on detection of parasite within RBC’s–deadliest parasitic infection
Toxoplasma gondii
sporozoan, blood and tissues; intracellular parasite; infects all vertebrate species (primary host is cat); infection of normal human host asymptomatic; immunocompromised or pregnancy aqcuired infections very dangerous; directly destroy cells, block blood vessels, cause necrosis
Leishmania species
flagellate, blood and tissues; 3 clinical types: cutaneous (ulcerating skin sores), mucocutaneous (sores in mucosal-dermal junction, multiple lesions), visceral (initially infect macrophages which migrate to the spleen, liver and bone marrow); transmission to humans is the bite of the sandfly