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Peptic Ulcer Disease > Proton Pump Inhibitors (PPIs) (-prazole) > Flashcards

Proton Pump Inhibitors (PPIs) (-prazole) Flashcards

1
Q

Examples

A

Lansoprazole

Omeprazole

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2
Q

MoA

A

Proton Pump of parietal cells
Inhibitor
Prevent acid secretion

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3
Q

Indications

A 
PUD
Reflux oesophagitis (GORD)
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4
Q

ADR

A 
GI disturbances
Risk C. diff infection
Hyponatraemia
Hypomagnesaemia
Leukopenia
Thrombocytopenia
Interstitial nephritis
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5
Q

Prescribing Advice

A 
IRREVERSIBLE
Reduced activation of Clopidogrel
Increased Warfarin effect
Rebound acid hypersecretion syndrome (RAHS)
MASKING OF GASTRIC CANCER SX
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Peptic Ulcer Disease (4 decks)

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