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Peptic Ulcer Disease > Histamine2 Receptor Antagonists (-tidine) > Flashcards

Histamine2 Receptor Antagonists (-tidine) Flashcards

1
Q

Examples

A

Cimetidine

Ranitidine

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2
Q

MoA

A

H2 Receptor in gastric parietal cells
Competitive antagonist
Reduce basal and stimulated acid output (90%)

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3
Q

Indications

A

2nd line PUD

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4
Q

ADR

A 
Diarrhoea
Confusion,
Depression
GYNAECOMASTIA
Mask Sx of gastric cancer
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5
Q

Prescribing Advice

A

Inhibitor of CYP450 dependent metabolism

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Peptic Ulcer Disease (4 decks)

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