protests 1 hemoflagellates kinetoplastea Flashcards
protists euks or proks
euks
protists taxonomy
kingdom- protozoa
excavata taxonomy
- kingdom- protozoa
- class- excavata
excavata aka
flagelates
excavata repro
asexual multiplication via binary fission
excavata motion
undulipodium eukaryote flagellum for locomotion
excavata contains what order
- kinetoplasts = haemoflagellates?
kinetoplast taxonomy
- kingdom- protozoa
- class- excavata
kinetoplasts id
- v large mitochondria (kinetoplast) at base of flagellum
- contins a lot of dan used to study dna editing
kinetoplasts includes what fams
- trypanosomatida
- leishmania
trypanosomatida taxonomy
- kingdom- protzoa
- class excavata
- order- kinetoplasts
- fam- trypanosomatida
trypanosome shape
- elongated spindle shaped cell w/ single nucleotide and flagellum from kinetoplast (anterior end)
trypanosome types
- amastigote
- promastitoge
- epimastigote
- trypomastigote
amastigote id
lacks flagellum
promastigote id
kinetoplast near anterior end
epimastigote id
kinetoplast immediately anterior to nuc
trypomastigote id
kinetoplast posterior to nucleus
trypanosomatida tranmission
from host to host by blood sucking instects
trypanosomatida organ/ cell effected
live in blood, lymph, and tissue spaces
salivarian trypanosoma taxonomy
- kingdom- protzoa
- class excavata
- order- kinetoplasts
- fam- trypanosomatida
- group- salivarian
salivarian trypanosoma trnamission
- saliva of vector, bite associated transmission
trypanosoma bruceli taxonomy
- kingdom- protzoa
- class excavata
- order- kinetoplasts
- fam- trypanosomatida
- group- salivarian
trypanosoma bruceli host
ruminants
trypanosoma stage
only stage a trypanosome
trypanosoma bruceli life cycle
tsetse takes bld meal -> trypomastigote injected into blood -> multiply by binary fission -> tsetse takes blood meal -> transform and multiply by binary fission in midgut -> leave midgut and transform into epimastigotes -> mult in salivary gland
trypanosoma bruceli transmission
tsetse saliva
trypanosoma bruceli organ/ cell effected
develop in bld plasma
trypanosoma bruceli dx
- African sleeping sickness (perivascular cuffing of lymphocytes in brain)
- fatal nagana dx
trypanosoma bruceli location
sub saharan africa
trypanosoma bruceli reservours
wild ruminants
trypanosoma congolense taxonomy
- kingdom- protzoa
- class excavata
- order- kinetoplasts
- fam- trypanosomatida
- group- salivarian
trypanosoma congolense host
ruminants
trypanosoma congolense life cycle
tsetse takes bld meal -> trypomastigote injected into blood -> multiply by binary fission -> tsetse takes blood meal -> transform and multiply by binary fission in midgut -> leave midgut and transform into epimastigotes -> mult in salivary gland
trypanosoma congolense transmission
tsetse saliva
trypanosoma congolense dx
fatal nagana dx
trypanosoma congolense location
sub saharan africa
trypanosoma congolense reserviour
wild ruminants
trypanosoma vivax taxonomy
- kingdom- protzoa
- class excavata
- order- kinetoplasts
- fam- trypanosomatida
- group- salivarian
trypanosoma vivax host
livestock
trypanosoma vivax transmission
biting flies other than tsetese saliva
trypanosoma vivax dx
- Acute – High parasitemia, mucosal & serosal hemor-rhages
- Chronic – Anemia, emaciated
trypanosoma vivax location
- subsaharan africa
- central and south america
trypanosoma vivax reserviour
- wild ungulates in Africa
- deer in americas
trypanosoma evansi taxonomy
- kingdom- protzoa
- class excavata
- order- kinetoplasts
- fam- trypanosomatida
- group- salivarian
trypanosoma evansi host
domestic animals
trypanosoma evansi transmission
- tabanidae (biting flies) saliva
- vampire bats saliva
trypanosoma evansi dx
surra
trypanosoma evansi location
- africa north of sahara
- Asia
- tropical america
trypanosoma equiperdum
- kingdom- protzoa
- class excavata
- order- kinetoplasts
- fam- trypanosomatida
group- salivarian
trypanosoma equiperdum host
horses
trypanosoma equiperdum life cycle
does not require intermediate host
trypanosoma equiperdum transmission
sexually transmitted dx of horse
trypanosoma equiperdum dx
dourine;
- swelling of genitalia and mucoid dc if acute
- circular silver dollar plaques on skin
- emaciation paresis, fever, death if chronic
trypanosoma equiperdum erradication
eradicated from us and Canada
trypanosoma salivarian group members
- trypanosoma brucei
- trypanosoma congolense
- trypanosoma vivax
- trypanosoma evansi
- trypanosoma equiperdum
stercorean trypanosoma taxnomy
- kingdom- protzoa
- class excavata
- order- kinetoplasts
- fam- trypanosomatida
group- stercorean
stercorean trypanosoma tranismssion
in feces of vector
trypanosoma cruzi taxnomy
- kingdom- protzoa
- class excavata
- order- kinetoplasts
- fam- trypanosomatida
group- stercorean
stercorean trypanosoma group members
- trypanosoma cruzi
- trypanosoma cervi
- trypanosoma thileri
- trypanosoma melophagium
trypanosoma cruzi lifecycle
Triatomine bug takes blood -> Pass trypomastigote in feces then enter cells at bite wound ->Transform into amastigotes ->Multiply in cells Transform into trypomastigotes and burst out of cell into blood -> Bug takes blood meal -> Epimastigotes in midgut ->Multiply -> Trypo-mastigotes in hindgut
trypanosoma cruzi host
humans, dogs, other mammals
trypanosoma cruzi transmission
- Triatomine bugs genera Triatoma, Rhodnius, Pan-strongylus
- Dogs & cats can also get it by eating infected rats
trypanosoma cruzi organ/ cell effected
cells and blood
trypanosoma cruzi dx
American Trypano-somiasis (Chaga’s Disease)
American Trypano-somiasis (Chaga’s Disease)
1 of the big 5 neglected parasite diseases in the USA
- Enters muscle & nerve cells causing mega-esophagus, megacolon, heart disease
- spread by trypanosoma cruzi
trypanosoma cruzi location
South & Central America, Texas, Arizona, New Mexico, California, Oklahoma
trypanosoma cruzi reserviours
- opossums
- armadillos
- rats
- g pigs
- cats
- racoons
- monkeys
trypanosoma cervi taxonomy
- kingdom- protzoa
- class excavata
- order- kinetoplasts
- fam- trypanosomatida
group- stercorean
trypanosoma cervi host
- reindeer
- white tailed deer
- elk
- mule deer
trypanosoma cervi location
alaska and florida
trypanosoma cervi pathogenesis
non pathogenic
trypanosoma theileri taxnomy
- kingdom- protzoa
- class excavata
- order- kinetoplasts
- fam- trypanosomatida
group- stercorean
trypanosoma theileri host
cattle
trypansoma theileri id
HUGE
trypanosome theileri transmission
tabanid flies
trypanosome theileri pathogenesis
non-pathogenic
trypanosoma melophagium taxnomy
- kingdom- protzoa
- class excavata
- order- kinetoplasts
- fam- trypanosomatida
group- stercorean
trypanosoma melophagium host
sheep
trypanosoma melophagium transmission
melophagus ovinus (sheep ked)
trypanosome melophagium location
worldwide
trypanosome melophagium pathogenesis
non pathogenic
leishmania taxnomy
- kingdom- protzoa
- class excavata
- order- kinetoplasts
- fam- leishmania
leishmania host
- dog main host
- human accidental
leishmania life cycle
Sandfly takes blood & injects promastigotes into skin -> Taken up by macrophages -> Transform into amastigotes -> Multiply in cells -> Sandfly takes blood & ingests infected macrophage -> Transform into promastigote in midgut -> Divide in midgut & migrate to probiscus
leishmania transmission
phlebotimine sandfly
leishmania organ/ cell effected
parasites of macrophage
usually affect skin but can be visceral (spleen and liver)
leishemia location
mainly
- caribbean
- subsaharan africa
- brazil
leishmania types
- amistigotes in vertebrates (macrophages)
- promastigotes in flies
leishmania infantum taxnomy
- kingdom- protzoa
- class excavata
- order- kinetoplasts
- fam- leishmania
leishmania infantum host
dogs and cats
leishmania infantum dx
- visceral leishmaniasis w/ cutaneous lesions
leishmania infantum reserviour
- dogs = major reserviours for human infection
- target of eradication in many countries
leismainia donovani taxnomy
- kingdom- protzoa
- class excavata
- order- kinetoplasts
- fam- leishmania
leishmania donovani huost
humans only
leishmania donovani dx
vesceral leishmaniasis
leishmania tropica taxnomy
- kingdom- protzoa
- class excavata
- order- kinetoplasts
- fam- leishmania
leishmania tropica hosts
- humans
- dogs
- rodents
- wild mammals
leishmania tropica dx
- cutaneous leishmaniasis
leishmania tropica location
Eurasia and africa
leishmania mexicana taxonomy
- kingdom- protzoa
- class excavata
- order- kinetoplasts
- fam- leishmania
leishmania mexicana dx
cutaneous lesions
leishmania mexicana location
the americas
leishmania mexicana reserviours
various animal reserviours
leishmania brazilienesis taxonomy
- kingdom- protzoa
- class excavata
- order- kinetoplasts
- fam- leishmania
leishmania brazilinesis dx
- mucocutaneous leishmaniasis
- horrible lesions that eat off your nose and lips
leishmania braziliensis location
- the americas down through Peru