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Move Sci Exam 1 > Proteoglycans > Flashcards

Proteoglycans Flashcards

0
Q

Small Leucine-Rich PGs (SLRPs)

A

Decorin, Byglycan, Fibromodulin, Lumican, Epiphycan

Slurp Dick&Balls For Leukemia, Elsie!

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1
Q

Large extracellular aggregating

A

Versican, Aggecan, Brevican, Neurocan

Larry Even Ate Veggies After Beating Nancy

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2
Q

Cell-Associated PGs

A

Serglycins, Syndecans, Betaglycan, CD44 Family, Thrombomodulin
(Cap. Gary Said, “Send Beatles’ CD’s There.”)

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3
Q

Basement Membrane PGs

A

Perlecan, HS & CS PGs, Bamacan

Bama Men Probably Go, “Play Hard Cool Pinball, ‘Bama!”

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4
Q

Nervous Tissue PGs

A

Phosphacan, Agin, NG2 PG

Nancy Told Peter Plausibly After Night Game 2

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5
Q

Versican fxn

A

fxn unknown

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6
Q

Aggrecan fxn

A

Creates osmotic swelling pressure in cartilage by attracting H2O

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7
Q

Versican Location

A

Smooth muscle cells

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8
Q

Versican Composition

A

Fibroblasts

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9
Q

Aggregan Location/Composition

A

Found in chains of KS & CS (compression); Binds to hyaluronan

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10
Q

Brevican Location

A

Nervous tissue

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11
Q

Brevican Function

A

Cell adhesion & migration

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12
Q

Neurocan Function

A

Cell adhesion & migration

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13
Q

Neurocan Location

A

Nervous Tissue

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14
Q

Decorin Location

A

One or two CS or DS chains

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15
Q

Decorin Function

A

Binds & regulates growth factors; modules cell function; regulates collagen fibrogenesis; interacts w/ various collagen types all over body

16
Q

Biglycan Location

A

Two GAG chains containing CS or DS

17
Q

Biglycan Function

A

Directs type VI collagen network assembly (skin & BV’s); Binds to complement to transform Growth Factor Beta

18
Q

Fibromodulin Location

A

One KS GAG chain

19
Q

Fibromodulin Function

A

Interacts with Type I & II collagen, binds to growth factors

20
Q

Lumican Location

A

One KS GAG Chain; found in cornea, muscle, intestine, cartilage

21
Q

Epiphycan Location

A

Found in epiphyseal cartilage (growth plates)

22
Q

Serglycins Function

A

Protein core of heparin - PGs regulate enzyme activity in secretory granules

23
Q

Syndecans Location

A

Cell membranes

24
Q

Syndecans Function

A

Contains heparan sulfate (HS); acts as receptor for heparin-binding factor

25
Q

CD44 Family Location/Function

A

Cell surface receptor for hyaluronan

26
Q

Thrombomodulin Function

A

Binds to thrombin (blood thinning?)

27
Q

Perlecan Location

A

Found in all tissues

28
Q

Perlecan Function

A

Unknown

29
Q

HS & CS PGs Location

A

Found in tall tissues

30
Q

HS & CS PGs Function

A

Unknown

31
Q

Agrin Function

A

Aggregates ACH receptors

32
Q

NG2 PG Location/Function

A

Found in Developing calls; fxn unknown

Move Sci Exam 1 (4 decks)

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