Proteoglycans

Question 0

Small Leucine-Rich PGs (SLRPs)

Answer 0

Decorin, Byglycan, Fibromodulin, Lumican, Epiphycan

Slurp Dick&Balls For Leukemia, Elsie!

Question 1

Large extracellular aggregating

Answer 1

Versican, Aggecan, Brevican, Neurocan

Larry Even Ate Veggies After Beating Nancy

Question 2

Cell-Associated PGs

Answer 2

Serglycins, Syndecans, Betaglycan, CD44 Family, Thrombomodulin
(Cap. Gary Said, “Send Beatles’ CD’s There.”)

Question 3

Basement Membrane PGs

Answer 3

Perlecan, HS & CS PGs, Bamacan

Bama Men Probably Go, “Play Hard Cool Pinball, ‘Bama!”

Question 4

Nervous Tissue PGs

Answer 4

Phosphacan, Agin, NG2 PG

Nancy Told Peter Plausibly After Night Game 2

Question 5

Versican fxn

Answer 5

fxn unknown

Question 6

Aggrecan fxn

Answer 6

Creates osmotic swelling pressure in cartilage by attracting H2O

Question 7

Versican Location

Answer 7

Smooth muscle cells

Question 8

Versican Composition

Answer 8

Fibroblasts

Question 9

Aggregan Location/Composition

Answer 9

Found in chains of KS & CS (compression); Binds to hyaluronan

Question 10

Brevican Location

Answer 10

Nervous tissue

Question 11

Brevican Function

Answer 11

Cell adhesion & migration

Question 12

Neurocan Function

Answer 12

Cell adhesion & migration

Question 13

Neurocan Location

Answer 13

Nervous Tissue

Question 14

Decorin Location

Answer 14

One or two CS or DS chains

Question 15

Decorin Function

Answer 15

Binds & regulates growth factors; modules cell function; regulates collagen fibrogenesis; interacts w/ various collagen types all over body

Question 16

Biglycan Location

Answer 16

Two GAG chains containing CS or DS

Question 17

Biglycan Function

Answer 17

Directs type VI collagen network assembly (skin & BV’s); Binds to complement to transform Growth Factor Beta

Question 18

Fibromodulin Location

Answer 18

One KS GAG chain

Question 19

Fibromodulin Function

Answer 19

Interacts with Type I & II collagen, binds to growth factors

Question 20

Lumican Location

Answer 20

One KS GAG Chain; found in cornea, muscle, intestine, cartilage

Question 21

Epiphycan Location

Answer 21

Found in epiphyseal cartilage (growth plates)

Question 22

Serglycins Function

Answer 22

Protein core of heparin - PGs regulate enzyme activity in secretory granules

Question 23

Syndecans Location

Answer 23

Cell membranes

Question 24

Syndecans Function

Answer 24

Contains heparan sulfate (HS); acts as receptor for heparin-binding factor

Question 25

CD44 Family Location/Function

Answer 25

Cell surface receptor for hyaluronan

Question 26

Thrombomodulin Function

Answer 26

Binds to thrombin (blood thinning?)

Question 27

Perlecan Location

Answer 27

Found in all tissues

Question 28

Perlecan Function

Answer 28

Unknown

Question 29

HS & CS PGs Location

Answer 29

Found in tall tissues

Question 30

HS & CS PGs Function

Answer 30

Unknown

Question 31

Agrin Function

Answer 31

Aggregates ACH receptors

Question 32

NG2 PG Location/Function

Answer 32

Found in Developing calls; fxn unknown