Proteins that Regulate Transcription Flashcards
1
Q
What are the 2 types of regulatory protein?
A
ACTIVATORS and REPRESSORS.
2
Q
What is the difference between a Transcription Factor and a General Transcription factor?
A
GTF: REQUIRED to initiate transcription at all promotors.
TFs: Proteins that STIMULATE OR REPRESS transcription, bind to promoter-proximal elements and enhancers in eukaryotic DNA.
- They are modular proteins
- They contain a SINGLE DNA BINDING DOMAIN and ONE OR MORE activation DOMAINS (for activators) or repression domains (for repressors).
3
Q
Do repressors sterically hinder binding sites?
A
NO!
They do not overlap or block anything else, they HAVE THEIR OWN BINDING SITES (not like in procaryotes - bacteria).
