Proteins structure Flashcards

1
Q

proteins are compounds containing what elements

A

C
H
O
N

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2
Q

building blocks protein

A

amino acids

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3
Q

which 2 groups do all amino acids contain

A

Amino - NH2/NH3+

Carboxylic Acid - COOH

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4
Q

what structurally differentiates each a/a from each other

A

unique side group

‘r group’

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5
Q

smallest a/a

A

glycine

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6
Q

what can glycine cross

A

BBB

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7
Q

body commonly uses 20 a/a for what

A

polypeptide synthesis

building blocks protein

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8
Q

how must a/a supplements be taken

A

EMPTY STOMACH better absorbed

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9
Q

what happens if take A/A supplement while eating high protein food

A

they will go to build muscle not specific therapeutic

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10
Q

beta brainwaves are for what

A

tense/ fight/flight

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11
Q

alpha brainwaves do what

A

relaxation, mindfulness

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12
Q

theta brainwaves do what

A

light sleep/just waking

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13
Q

delta brainwaves do what

A

deep sleep, dreaming

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14
Q

which brainwaves in meditation

A

alpha

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15
Q

what is threonine’s nickname

A

the ‘now’ a/a - helps alpha

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16
Q

dipeptide made up of

A

2 a/a

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17
Q

tripe peptide made up of

A

3 a/a

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18
Q

oligopeptide made up of

A

several a/a

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19
Q

polypeptide made up of

A

50+ a/a

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20
Q

how many a/a in a protein

A

a few dozen to several hundred

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21
Q

2 conditions that could denature proteins

A

heat

acid

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22
Q

what 3 things happen to a denatured protein

A

uncoiling of structure -
loss of shape
loss of function

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23
Q

which bonds break in denatured protein

A

disulphide

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24
Q

what is main solvent of body

A

water

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25
what happens if not enough water in body
impaired chemical reactions | = fatigue
26
7 functions of protein
``` body's building blocks enzymes hormones immunoproteins transport proteins acid base regulators fluid balance regulators ```
27
2 stages of bone building
cells lay a matrix from collagen | then fill with mineral crystals
28
which protein does body use for building itself
collagen
29
Ex of enzymes
digestive enzymes
30
role of enzymes
change substances without being altered themselves | can act as catalysts
31
what type of cofactors do enzymes req
vitamins minerals
32
what if enzymes lack cofactors
will still work but will be impaired -use more energy - fatigue
33
what 3 substances can hormones be derived from
cholesterol a/a polypeptides
34
whats makes thyroid hormones
Tyrosine + Iodine
35
which a/a is the base for: dopamine norepinephrine epinephrine
tyrosine
36
which a/a is base for melatonin
tryptophan
37
what is protein structure of insulin
2 polypeptide chains
38
what is protein structure of glucagon PTH calcitonin
one polypeptide chain
39
if lacking in tyrosine or iodine what could you have
faulty thyroid
40
symptoms of low thyroid
fatigue hair loss weight gain feel cold
41
what happens to immunity if low protein
compromised
42
2 types immunoproteins
immunoglobulins | antibodies
43
ex immunoglobulin
GAMED
44
which cells produce immunoglobulins
plasma cells | lymphocytes
45
which cells produce antibodies
B cells
46
what are the messengers of the innate immune system
cytokines
47
role of T reg cells in acquired immunity
help end immune response/prevent harmful reactions occuring
48
other term for acquired/adaptive immunity
humoral
49
which type of immunity uses antibodies
acquired/immunity
50
other type immunity
innate
51
what do transport proteins do
combine with other substances in blood or cells to provide a mode of transport
52
what transports calcium, zinc, vitamin B6
albumin
53
what transports bit A
retinol binding protein
54
what transports )2
Hemoproteins
55
what transports iron
transferrin
56
what transports copper
ceruloplasmin
57
how electrically do proteins act as acid-base regulators
PROTEINS - attract HYDROGEN+
58
proteins maintain acid-base balance in body fluids by
accepting/releasing H+
59
what do proteins attract that helps them regulate fluid balance
water
60
what happens if plasma proteins leak out of capillary walls faster than they can be reabsorbed
fluid collects in tissues | oedema
61
3 protein-related causes of oedema
excessive protein losses - kidney disease/large wounds liver disease - inadequate protein synthesis inadequate dietary intake
62
what are conjugated proteins
proteins joined to non-protein components
63
2 ex conjugated proteins
glycoproteins | proteoglycans
64
what are glycoproteins
proteins bound to carbohydrates
65
3 ex glycoproteins
collagen elastin bone matrix
66
where are proteoglycans found
hyaluronic acid chondroitin sulphate keratin sulphate
67
is nitrogen in protein and fat
no just protein
68
cells synthesise proteins according to what
genetic info provided by DNA in nucleus of each cell
69
in protein synthesis DNA dictates the order of what
which a/a linked together to form given protein
70
what is protein turnover
within each cell, proteins continually being made/broken down
71
when proteins break down they free...
amino acids to join the general circulation
72
what 2 types make up amino acid pool
diet derived a/as | a/a's freed during protein turnover
73
when energy & protein intake exceeds need, a/a may make what in body
fat
74
what is process of storing a/a as fat
deaminated - nitrogen excreted remaining C fragments converted to fat & stored
75
where do we excrete nitrogen
urea cycle