Proteins & Amino Acids Flashcards

1
Q

Why is insufficient protein in the blood problematic?

A
  • Lack of protein decreases fluid return to capillary due to low oncotic pressure
  • Results in edema
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2
Q

What are essential amino acids?

A
  • Need to taken in through diet because body cannot make them
  • Some are also conditionally essential, they may need a precursor to be made or perhaps children need more of them`
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3
Q

How are proteins related to allergies?

A
  • Protein may be absorbed intact
  • First time, immune system is stimulated
  • Consumption again causes recognition as a foreign substance
  • An immune response is mounted and an allergic reaction occurs
  • This response may be life-threatening if anaphylaxis occurs and there are breathing difficulties or a huge drop in BP
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4
Q

What are recent studies finding about infants and peanut consumption?

A
  • Early introduction of peanuts significantly decreased the frequency of developing a peanut allergy
  • Immune system is less mature and less likely to react adversely
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5
Q

What is the structure of proteins?

A
  • Involves an amino group with a side chain, and a carboxylic acid group
  • Amino group contains nitrogen
  • Structure directed by DNA
  • Form polypeptides with other amino acids
  • Improper protein synthesis can result in altered polypeptide shape (ex. sickle cell anemia)
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6
Q

What are “limiting amino acids”?

A
  • A shortage of an amino acid limits the ability to synthesize a protein that is high in this amino acid
  • Needs to be accessible from the amino acid pool
  • All protein is functional, cannot be stored
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7
Q

What are proteins in the amino acid pool used for?

A
  • Energy production
  • Synthesis of glucose or fatty acids
  • Synthesis of nonprotein molecules containing nitrogen (ex. NTs and DNA)
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8
Q

What is negative and positive nitrogen balance?

A
  • Nitrogen intake does not equal nitrogen output
  • Negative: nitrogen intake < nitrogen output, so total body protein decreases as when someone is ill
  • Positive: nitrogen intake > nitrogen output, so total body protein increases, as during pregnancy or growth
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9
Q

What are sources of dietary protein?

A
  • Meats, fish, eggs and dairy products - main sources of animal proteins
  • Plant sources of protein - legumes, vegetables and grains
  • The source of protein will determine what other nutrients are consumed with it
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10
Q

What is the primary source of protein for most of the world’s population?

A
  • Grains and vegetables
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11
Q

Plant sources of protein tend to be less ____.

A

Expensive

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12
Q

What is protein complementation?

A
  • Says meat contains all the amino acids we need
  • Most plants, other than soy, supply incomplete proteins
  • Need to choose plants containing complementary amino acids to provide all essential AAs (ex. rice and beans)
  • No evidence to support this, no need for complementation for vegetarians/vegans
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13
Q

Are there differences in protein quality among different sources?

A
  • Isolated soy protein and egg white easily digestible and accessible protein
  • Many plant proteins are harder to access
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14
Q

What is the association of animal and plant protein intake with mortality?

A
  • High animal protein intake was positively associated with mortality and high plant protein intake was inversely associated
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15
Q

What time of day is it best to consume protein?

A

Protein consumption should be evenly distributed over three meals, as it is associated with greater muscle strength

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16
Q

What is phenylketonuria?

A
  • Infant was found to have phenylketonuria or PKU
  • Genetic disease where the gene for phenylalanine hydroxylase (PAH) is non-functional
  • Common mutation for classic PKU, change from G to A at splice site in mRNA for the PAH gene, yields truncated protein (loss of 99% of activity)
  • Phenylalanine not converted into tyrosine, becomes phenylketones, which are toxic to the brain
  • Must be detected early to prevent brain damage
  • Requires low Phe diet for life, cannot consume aspartame
17
Q

What are benefits of vegetarianism?

A
  • Lower body weight
  • Lower incidence of diabetes, CVD, hypertension, some cancers
  • Need to ensure nutrient needs are met
18
Q

What nutrients do vegans need to pay extra attention to?

A
  • Protein, vitamin B12, calcium, vitamin D, iron, since, and omega-3