Proteins Flashcards
1
Q
Describe haem groups
A
Protoporphyrin ring and iron atom
2
Q
Describe myoglobin
A
Alpha helical
Globular
3
Q
Describe haemoglobin
A
Alpha-2, Beta-2 tetramer
4
Q
Describe fetal haemoglobin
A
Alpha-2, gamma-2
Higher affinity for oxygen than HbA (adult)
5
Q
What forces maintain primary and secondary protein structure?
A
Covalent/peptide
H-bonds = secondary
6
Q
What forces, in decreasing bond enthalpy, maintain structure in tertiary/quaternary proteins?
A
Covalent (disulphide) Ionic H-bonds Van dear Waals Hydrophobic effect
7
Q
Describe fibrous proteins
A
Long strands
Single type secondary structure
Support/shape/protection
Collagen
8
Q
Describe globular proteins
A
Compact
Several types secondary structure
Catalyst
9
Q
What is the isolectric point? If the pI is greater than 7, what kind of protein is it?
A
The pH at which there is no overall net charge
Basic protein, protonated
