Proteins Flashcards

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1
Q

What is the primary structure of a protein?

A

The linear sequence of amino acids

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2
Q

What is the secondary structure of a protein?

A

The chain folds into alpha helices and beta pleated sheets

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3
Q

What is the tertiary structure of a protein?

A

The overall 3D shape of the protein through the secondary structures and interactions between the amino acid side chains

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4
Q

What is the quaternary structure of a protein?

A

Multiple proteins with unique tertiary structures interact in a multi protein complex

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5
Q

What are chaperones? How do they work?

A

Proteins that facilitate the folding of other proteins. They bind to and stabilize unfolded/partially folded proteins and stop aggregation and degradation. They also poke the protein back into the right shape if it starts to misfold

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6
Q

What types of cells are chaperones found in?

A

All cells, all types, in every part. Their structure and function is conserved in all organisms

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7
Q

Why do proteins bind to other things?

A

It changes their shape and turns them on or off temporarily. When they detach, it goes back to its original shape

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8
Q

What is complementarity?

A

Proteins have a lock and key fit with their binding partners and use transient bonds (H-bonds, van der Waals, ionic)

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