Proteins Flashcards
To be well versed in proteins
Kind of polymer
Heteropolymer
Minimum number of amino acids
50
Kind of molecules and where found
Macromolecules found in acid insoluble pool
Most abundant protein in animal world
Collagen
Most abundant protein in biosphere
RuBisCo Ribolose Biphosphate Carboxylase - oxygenase
Involved in carbon fixing during photosynthesis In which CO² to glucose
Which gives us the positional information about the protein
Primary structure
Which is the N terminal in proteins
The first amino acid or the one on the left
Which is C terminal in proteins
The last amino acid or the one on the right
Two types of secondary proteins
Alpha Felix and beta pleated sheath
There is also a collagen helix
Type of helix observed in proteins
Right hand
Cause of secondary structure helix
Formation of hydrogen bonds between every forth amino acid
The hydrogen bond is formed between hydrogen and a highly electro negative atom (N, O, F)
Example of alpha helix
Alpha keratin
What causes beta pleated sheath
When there are hydrogen bonds formed between hydrogen two or more Polypeptide chains
The hydrogen bond is formed between hydrogen and a highly electro negative atom (N, O, F)
Example of beta pleated sheath
Fibroin the protein if silk
Collagen helix
The Polypeptide coil of collagen helix is strengthened by establishing hydrogen bond
Cause of locking effect in collagen helix
Hydroxyproline and proline
View of tertiary protein
3D
How does an active site form
By bringing distant amino acids side chains closer forming an active site where the substrate will attach
Most important structure in relation to biological functions
Tertiary structure
Example of tertiary structure
Myoglobin
Haemoglobin breakdown at Quaternary structure
Four helical Polypeptide chains. Two alpha chains, two beta chains
Collagen
Intracellular group substance
Long fibroid structural proteins main compound of cartilage, ligaments, tendons bones and teeth
Trypsin
Enzyme
Insulin
Hormone
Frederick Sanger studied it
