Proteins Flashcards
Monomer of proteins
amino acids
Polymer of proteins
Polypeptide
Amino acid structure
amino group + C + carboxyl group + H + R group (side chain)
How does the sequence of amino acids effect a protein?
Changes the structure and function
Protein functions
- Signalling
- Structural
- Transporting
- Enzymatic
- Regulatory
- Storage
- Defence (antibody)
Primary protein structure
Amino acids form polypeptide chain with peptide bonds
Secondary protein structure
Hydrogen bonds between atoms in polypeptide backbone
- Alpha helix
- Beta folded sheet
Tertiary protein structure
Stabilized by R group interactions
- Hydrophilic and hydrophobic clustering
- Hydrogen bonds
- Ionic bonds
- Disulphide bridges
- Covalent bonds
Quaternary protein structure
Interactions between multiple polypeptide chains
- Hydrophilic and hydrophobic clustering
- Hydrogen bonds
- Ionic bonds
- Disulphide bridges
- Covalent bonds
- Van der Waals forces
Globular proteins
Round shape
Polar
Water soluble
Irregular amino acid sequence
Sensitive to environmental changes
Fibrous proteins
Long strand-like shape
Non-polar
Not water soluble
Repetitive amino acid sequence
Resistant to environmental changes
Globular protein examples
Haemoglobin- transports O to blood for aerobic respiration
Insulin
Fibrous protein examples
Collagen- main component of connective tissue