Proteins Flashcards
What are proteins composed of?
Carbon, hydrogen, oxygen and nitrogen
(Body’s main source of nitrogen - 16% weight of protein)
What are amino acids?
Building blocks of protein
Proteins make about 20 amino acids
What is the basic stricture of an amino acid?
central carbon atom, hydrogen atom, amino group, acid group
Fourth bond is distinct side group chain
What are non-essential amino acids?
Body can synthesise them itself
Production is reliant on adequate precursors
11 amino acids
What are essential amino acids?
body cannot make in sufficient amount, must be consumed in diet
9 amino acids
What are conditional essential amino acids?
if body fails to supply/cannot make conversions - a non-essential can become conditionally essential
What is a peptide bond?
A peptide bond link amino acids end to end in a variety of forms
How are amino acid chains formed?
Condensation reactions connect amino acids
Dipeptide - 2 amino acids
Tripeptide - 3
Polypeptide - 50-100
What is the primary structure of amino acid sequence?
Can be linked in a variety of sequences
Determines identity of protein
What is the secondary structure of amino acid sequence?
Determined by weak electrical attractions within polypeptide chain
Positively charged hydrogen atoms attract negatively charged oxygen atoms
Sections twist and fold - strength and identity
What is the tertiary structure - polypeptide tangles?
occurs as long chains that fold/twist into complex tangled shapes
Forms shape to perform function, max stability
What is protein denaturation?
First step in protein breakdown, uncoiling/losing shape of protein - frees amino acids
Occurs when proteins are subject to heat, acid, etc
What are the major gastric enzymes for protein?
hydrochloric acid
Pepsin
Rennin
How are proteins absorbed and transported?
Once inside intestinal cells, amino acids are transported to liver via portal vein
Liver responsible to either
- oxidise for energy
- build new proteins in body
- use as spare spart for other nitrogen containing compounds
What happens in stomach during digestion?
hydrolysis, hydrochloric acid denatures tangles
Converts pepsinogen (inactive) into pepsin (active)
Pepsin cleaves proteins into smaller amino acids