Proteins Flashcards
Parts of protein?
Amino group(NH3+), Carbon, Carboxyl group (COO-), Side chain
What is tyrosine’s precursor?
Phenylalanine
What is cystein’s precursor?
Methionine, serine
What is proline’s precursor?
Glutamate
What is arganine’s precursor?
Glutamine or glutamate, aspartate
What is glutamine’s precursor?
Glutamate, ammonia
What are different structure levels of protein (4)?
-Primary: Amino acid code
-Secondary: Hydrogen bonds in b-pleated sheets and a-helix
-Tertiary
-Quaternary
How do blood proteins affect fluid balance?
Albumin and globulin attract water, increasing fluid retention.
-Protein deficit decreases albumin and globulin which decreases oncotic pressure causing an edema.
*Oncotic pressure= pull extracellular fluid from capillary beds back into venous capillaries
How do proteins affect acid-base balance of the blood?
Proteins are buffers by accepting and donating H ion capability. High H ion concentration =low pH
-In acidic conditions, they pick up extra H ions
-In alkaline conditions, the donate H ions
What are some factors influencing dietary AA utilization?
Adequate energy intake:
-When intake < needs, † AA oxidation
Adequate CHO intake:
-When intake < needs, † AA use for gluconeogenesis
Protein qualitv:
-When ~ # EAA or [EAAJ, 1 AA oxid. &/or glucose/fat syn
Protein intake vs. protein req.:
-When protein intake > protein needs, † AA oxid. &/or
glucose/fat syn.
Physiological status:
• When † body protein (growth, preg, lact), † AA incorp.
• When y body protein (cancer, aging, fasting, trauma, hypermetabolism), ~ AA incorp
What happens with excess protein intake?
-Increase kidney work to remove NH3 (diuretic)
-Increase Ca loss esp. if excess animal protein
-Increase obesity & CHD ris excess preotein is animal (increase sat fat, fat, cholesterol)
-Increase cancer of colon, breast, pancreas, & prostate if excess animal protein
Anabolic vs catabolic
Anabolic build up. Catabolic break down
Anabolic use of AA
Plasma proteins, peptide hormones, protein secretions, enzymes, immune proteins, tissue proteins and N containing compounds
What is ARG used for?
Nitric oxide synthesis and vasodilation
Glucose alanine cycle