proteins Flashcards
what is an amino acid?
a monomer which makes up proteins
what does the shape/function of a protein depend on?
sequence, type and number of amino acids
how many amino acids are there?
20
what is the general structure of an amino acid?
- central carbon
- NH2 amine group on left
- COOH carboxylic acid group on right
- H on bottom
- R group on top
how are proteins joined?
peptide bonds
describe how a peptide bond forms
- hydroxyl of carboxylic acid and hydrogen of amine group are lost (1 water molecule)
- remaining carbon and double oxygen, bond to nitrogen of adjacent amino acid
- water is released
- condensation reaction
describe the primary structure of a protein
- sequence of amino acids
- peptide bonds
describe the secondary structure of a protein
- initial folding of polypeptide chain
- hydrogen bonding
- alpha helix or beta pleated sheets
describe the tertiary structure of a protein
- overall 3D shape
- hydrogen & ionic bonds
describe the quaternary structure of a protein
- 2+ polypeptide chains stacked to form a single protein molecule
- hydrogen bonding & disulfide bridges
what is a globular protein?
- almost spherical
- soluble
- metabolic functions
what is a fibrous protein?
- regular amino acid sequence
- insoluble
- structural functions
describe the structure of elastin
- fibrous
- short sequences of 3-9 amino acids
- flexible
- recoils after being deformed
- insoluble
describe the function of elastin
- allows tissues in the body to shrink out and back
e.g. bladder, lungs
describe the structure of collagen
- fibrous
- triple helix
- flexible
- no stretch
- insoluble
describe the function of collagen
- provides structural support
e.g. tendons, cartilage
describe the function of keratin
- fibrous
- provides support and protection for hair, skin and nails
- insoluble
describe the function of insulin
- globular
- allows glucose to enter cells
- maintains glucose conc
- specific, fixed shape
describe the structure of haemoglobin
- globular
- iron haem group
- 4 polypeptides
- conjugated
- 2 alpha and 2 beta subunits
- soluble
describe the function of haemoglobin
- transports oxygen around the body
describe the function of enzymes
- globular
- catalyses chemical reactions
e.g. amylase