protein transporters Flashcards
membrane proteins
major component in membranes but come in a large variation depending on junction
what are some functions of membrane proteins
-signal transduction (communication)
-structure/ cytoskeleton, extracellular matrix
-permeability
-connection to other cells
what molecules can move across membrane
gasses- CO2, O2, N2
small uncharged molecules
hydrophobic moelcules
water- but slow (polar uncharged small)
what molecules cant move across membrane
large uncharged polar molecules (glucose)
large charged polar (AA, ATP)
ions- anything with a charge
what type of protein transporters are gated
channesl
what are the three types of protein transporters
channels
transporters
ATP powered pumps
what are the 3 types of tranporters
uniporters
symporter
antiporter
speed of protein tranporters
channles > transporters > ATP powered pumps
links one molecule going down concentration gradient with another goin up concentration gradient
symporter
both molecules moving in opposite direction, same concentration gradient
antiporter
both molecules moving in same direction/ opposing concentration gradients
symporter
uniporter carrier proteins
facilitated
no energy
down concentration gradeint
how does a uniporter- GLUT 1 work
has an outward and inward facing conformation
-glucose binding makes the conformation inward facing toward cytosol
couple transport with another cargo moving in the same direction
symporter
symporters and antiporters
binding site for two substances
conformational change only when both bound
