ion pumps

Question 1

what is the purpose of ion pumps

Answer 1

general maintenance of membrane potentials
that are needed later for cotransport, pH balance, signaling, etc

Question 2

what are the four types of pumps

Answer 2

P,
V,
F,
ABC transporter

Question 3

which ion pumps are structurally different

Answer 3

p and v

Question 4

which ion pumps share functional similarity

Answer 4

p and v

Question 5

which ion pumps are structurally similar

Answer 5

v and f

Question 6

which ion pumps are functionally different

Answer 6

v and f

Question 7

which ions pumsp are fucntionally and structurally different

Answer 7

p and f

Question 8

p type pumps

Answer 8

structurally simple
-has phosphorylated intermediate where the pump is phosphorylated
-results in two confromational states E1 and E2
-used for many different ions- calcium, potassium, sodium, etc

Question 9

what kind of pump is the na k pump

Answer 9

p type pump

Question 10

what amino acid is phosphorylated in the na/k pump

Answer 10

asparated in the E1 state

Question 11

how do v type pumps change and get their energy

Answer 11

by ATP no phosphorylation intermediate

Question 12

where are v type pumps found

Answer 12

in lysosomes, golgi, secretory vesicles, plant vacoules, and cells that secrete H+

allows them to create an acidic enviroment

Question 13

what do v type pumps pump

Answer 13

H ions/ protons against htier concentrations gradeint

Question 14

f type pumps

Answer 14

also pumps h ions like v type pumps but pumps in reverse
generates ATP- ATP synthase
uses H moving down concentration gradient to make ATP

Question 15

where are f type pumps found

Answer 15

in mitochondria and chloroplasts

Question 16

ABC superfamilty of pumps

Answer 16

ATP binding cassette
not and ion pump
trasnports phospholipids, lipophilic drugs, cholesterol, and a few other small molecules

Question 17

can detoxify certain tissues

Answer 17

ABC pumps

Question 18

ABC pumps fcats

Answer 18

has four subunits, uses ATP energy

Question 19

what do ABC proteins do

Answer 19

export a wide variety of drugs and toxins from cells
about 50 ABP mamallian proteins

Question 20

where do ABC proteins localize in eukaryotes

Answer 20

to the plasma and intracellular organelle membranes
-in and out of cells and within cells

Question 21

where are ABC proteins highly expressed

Answer 21

in liver
kidney
intestines

Question 22

what do some ABC pumps act as

Answer 22

flipases- flip phospholipids

Question 23

what ABC proteins contian additional regulatory domtains

Answer 23

cystic fibrosis transmembrane regulator
this is nto actually a pump but a chloride channel

Question 24

chloride ABC channel where and what it does

Answer 24

the dephosphorylated state is closed facing the inside
phosphorulation removes the r domain gate thingy
ATP binds and it is open changing confromation and chloride can go through