Protein Sorting Signals Flashcards

1
Q

Mitochondria

A

H2N

N terminal hydrophobic a-helix

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2
Q

Nucleus

A

KKKRK

Lys/Arg rich

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3
Q

Peroxisome

A

SKL

N terminal apolar

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4
Q

ER signal (from ribosome)

A

H3N

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5
Q

Lysosomes

A

Mannose 6 phosphate

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6
Q

Secretory vesicle

A

Trp rich domain

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7
Q

Golgi to RER

A

KDEL

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8
Q

Cell membrane

A

N terminal apolar region

Stop transfer sequence

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