Protein Metabolism Flashcards
what is HSA human serum albumin
most abundant blood protein
what is a disintegrin
can break down integrin
what is metalloproteinase
metal component in protein enzyme
build up of two proteins in the brain can cause what
alzheimers
what are amino acids
building blocks of protein
how many amino acids in human body
20
what is involved in formula of alpha amino acid
main body, side chain, carboxyl group, amino group
when do amino acids form proteins
when they are joined covalently in a row
what is function of protein primary structure
important for function and 3-d shape
what is function of protein secondary structure
cause folding - beta sheets and alpha helix
what is function of protein tertiary sturcture
polypeptide chains become functional
what is function of protein quaternary structure
complex assembly of multiple polypeptide chains into single functional preotin complex
what do enzymes do
speed up rate of reaction but dont alter outcome
how can enzymes effect reaction rate
pH, temp, enzyme conc, substrate conc
info on proteins in onenote as too many
what is proteomics
biochem meets com sci, field relies heavily on bioinformatics
what are 2 key components of gastric juice needed for protein breakdown
HC1 and pepsinogen
where is Hc1 secreted
gastric glands
where is pepsinogen secreted
gastric glands
amino acids can be catabolised aerobically to produce what
CO2 and ATP
proteins in the human body are in a constant state of
muscle protein synthesis and breakdown
in a fasted state
muscle protein breakdown exceeds protein synthesis
in a fed state
protein synthesis exceeds protein breakdown
does exercise increase muscle hypertrophy
no but does inc mitchondrial factors
what is deamination
removal of amino acid from a molecule
what is transamination
transfer of one amino group from one molecule to another
what is important about transamination
its reversible
how many AA’s can our body synthesize
11/20
?/20 amino acids can be converted to glucose
18
what are the two ketogenic AA’s that cant be synthesized
leucine and lysine
what is total amino acid concentration in plasma
3-4mmol/L
