Protein Entry into the Mitochondria Flashcards
1
Q
The mitochondrial genome…
A
encodes only 14 proteins!
-others need to be transported in
2
Q
They have a signal sequence!
A
-made of positively charged lysines and arginines
-Transported via two protein translocases TOM and TIM
-chaperone proteins prevent backsliding in translocation and help protein folding
-signal peptidase cleaves signal sequence
-encoded in nuclear DNA
-proteins transported in linear form
