Protein 1 Flashcards
What is the structure of amino acids?
Glycerol backbone, plus a side group which varies ( 20 different amino acids)
More complex than carbs or fats
What element makes protein different from other nutrients ?
Nitrogen
Structure of proteins
Amino acids can be linked end to end (dipeptide, tripeptide, polypeptide (10 or more))
Function is determined by shape
Essential amino acids
Can’t be made by body, must be eaten
9 essential amino acids
( a few are conditionally essential, wounds, premies…)
Denaturation
Disruption of stability, proteins uncoil and loose shape,happens in stomach acid
Ex: cooking eggs
Can not be undone
Body uses –% of protein for energy
25%
Proteins are continually being broke. Down and remade
Nitrogen balance
Positive& negative N balance
N in = N out
Positive, children & pregnant women
Negative: fasting or starving
Protein digesting
Mouth
stomach (hydrochloric acid denatures
Small I: hydrolysis reactions, peptidase enzymes
Role of protein in body
Structural: muscles , bone, teeth, tendons, cartilage, blood, vessels
Enzymes
Transporters, ex: hemoglobin, lipoproteins
Enzymes
Are proteins
Catalyze all of life’s processes
Not altered by the rxns they facilitate
Proteins as acid base buffers
Gather up acid if pH too low, release acid if pH too high
PH must be between 7.36-7.44?
Proteins as antibodies
Defend
Low protein means deceased immune response
Hormones
Sterols, glucagon, insulin
Proteins fxns in body
Structural Enzymes Hormones Fluid balance (volume and composition of body fluid) Acid base balance: Transportation Antibodies Energy
% of intake
10-35%
Body can not store protein
Marasmus
Protein energy malnutrition
Chronic inadequate intake
6-18 months
Very skinny, muscles/heart weaken,
Impaired brain devel., low temp, growth ceases
Reversible if caught in time: 1. Fluid & electrolyte balance, 2. Nutrition and warming
Kwashiorkor
18months - 2 years when weaned from breast
Lack of proteins and hormones cause fluids to leak into interstitial spaces
Edema of limbs & face , bulging belly from fatty liver
Excess protein
Obesity, atherosclerosis, heart disease, worsen kidney disease, increases urinary calcium excretion
Adds saturated fat
RDA
.8 gm/ kg of body weight , 10-35%
Most ppl get too much
1oz=7g protein
Need ample fat and carbs, otherwise body breaks down own muscles b/c body’s top priority is ENERGY
High quality proteins
Must Contain: all essential amino acids, nitrogen containing amino groups & energy to synthesize the other
Animal foods, combined plant foods
Amino acid comp: cells need all simultaneously
Protein quality: Digestibility
Depends on protein source + other foods eaten
Animal: 90-99%
Plant: 70-90%
Soy: >90%