Protease Inhibitors Flashcards
1
Q
Protease Inhibitors
A
Lopinavir
Ritonavir
Indinavir
2
Q
Protease Inhibitors: S/E
A
Hyperlipidemia, Hyperglycemia (insulin resistance) causes increased incidence CVD in HIV pts, Fat redistribution
3
Q
Indinavir S/E
A
Kidney stones (hydration important)
4
Q
Ritonavir
A
Inhibits cytochrome p450
Mainly used as a booster combined with other PIs
Eg: Ritonavir/Lopinavir = Kaletra