Prostatitis Flashcards
NIDDK/NIH classification
I Acute bacterial prostatitis
II Chronic bacterial prostatitis
III Chronic pelvic pain syndrome (CPPS): chronic abacterial prostatitis
IIIA Inflammatory CPPS: white blood cells (wbc) in expressed prostatic secretions (EPS), postprostatic massage urine (VB3), or semen
IIIB Non-inflammatory CPPS: no wbc in EPS, VB3, or semen
IV Asymptomatic inflammatory prostatitis (histological prostatitis)
segmented urine culture
VB1: first 10-15ml of urine voided
VB2: mid-stream urine collection of 10-15ml
EPS: the prostate is massaged whilst holding a sterile container below the glans to catch secretions
VB3: first 10-15ml of urine voided following prostatic massage
symptoms of type II prostatitis
symptoms persist for 3 months or more
recurrent UTI
pelvic pain and voiding dysfunction
uropathogens in urine samples or blood
organisms in bacterial prostatitis
90% gram -ve ecoli
proteus, kleb.
10% enteroccous
symptom score in prostatitis
three main domains
NIH chronic prostatitis symptom index NIH CPSI
Pain - location freq severity
urinary symptoms - voiding, storage, impact on ADL
Impact on QOL
symptom score in prostatitis
three main domains
how many questions each
NIH chronic prostatitis symptom index NIH CPSI
Pain - location freq severity
urinary symptoms - voiding, storage, impact on ADL
Impact on QOL
4 on pain
2 on luts
3 on QOL
symptom score in prostatitis
three main domains
NIH chronic prostatitis symptom index NIH CPSI
Pain - location freq severity
urinary symptoms - voiding, storage, impact on ADL
Impact on QOL
treatment acute bacterial prostatitis
secondary care IV gent 7mg /kg urine culture 2 sets blood cultures review at 48 hours max 72 hours can step down to co trimoxazole or ciprofloxacin
treatment chronic bacterial prostatitis
quinolone for 4-6 weeks
alpha blockers
prostate cancer UK treatment algorithm for CBP
antibiotic 4-6 weeks, analgesia, alpha blockers review 4-6 weeks if symptoms ongoing and no response abx or no bacteria consider abuse if some response further abx otherwise treat pain luts sexual problems psychosocial problems
prostatic abscess mortality fever perineal pain luts
mortality 1-16% fever 30-72% perineal pain 20% urinary retention 1/3 luts in 96% of cases need imaging trus ct or mri to confirm
guidelines abcess more or less than 1cm
<1cm conservative >1cm us drainage and antibiotics if doesn't improve CT scan if localised to prostate TUR drainge if extra prostatic penetration open drainage
complications abscess
fistulation in bladder, urethra, rectum or perineum
severe sepsis
septic pul emboli and meningitis
epididymorchitis risk factors for STI
age under 35 and sexually active new partner 60 days multiple partners MSM sexual partner with STI prev history of STI inconsistent or no condom use outside of a mutually monogomous relationship
trust epididymitis guideline
STI high risk
cef 500mg IM one dose
100mg bd doxy 2 weeks
STI low risk
co trimoxazole if GFR above 30 960mg bd , caution use other meds raise pottasium
if egfr less than 30
ciprofloxacin 500mg od