Prostate Cancer Flashcards
Prostate specific antigen is produced from
Secretory epithelium of prostate gland
PSA is necessary for
Liquéfaction of seminal coagulum
Weight of PSA
32kD glycoprotein
In blood PSA is bound to
Alpha 2 macroglobulin
Alpha 1 anti trypsin
Serum value of PSA is
1-5units/L
Above 10 units/L is indicative of
Prostate cancer
Acid phosphatase hydrolyses phosphoric acid ester at pH between
4-6
Serum value of ACP
2.5-12 U/L
ACP is secreted by
Prostate cells
RBCs
Platelets
WBCs
Prostate isoenzyme is inactivated by
Tartaric Acid
ACP level is increased in
Prostate cancer
Bone metastasis of prostate cancer ( highly elevated)
Acid phosphatase hydrolyses
Phosphoric Acid Ester
Prostate acid phosphatase is an important
Tumor marker