Prostate Cancer Flashcards

1
Q

Prostate specific antigen is produced from

A

Secretory epithelium of prostate gland

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2
Q

PSA is necessary for

A

Liquéfaction of seminal coagulum

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3
Q

Weight of PSA

A

32kD glycoprotein

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4
Q

In blood PSA is bound to

A

Alpha 2 macroglobulin

Alpha 1 anti trypsin

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5
Q

Serum value of PSA is

A

1-5units/L

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6
Q

Above 10 units/L is indicative of

A

Prostate cancer

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7
Q

Acid phosphatase hydrolyses phosphoric acid ester at pH between

A

4-6

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8
Q

Serum value of ACP

A

2.5-12 U/L

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9
Q

ACP is secreted by

A

Prostate cells
RBCs
Platelets
WBCs

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10
Q

Prostate isoenzyme is inactivated by

A

Tartaric Acid

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11
Q

ACP level is increased in

A

Prostate cancer

Bone metastasis of prostate cancer ( highly elevated)

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12
Q

Acid phosphatase hydrolyses

A

Phosphoric Acid Ester

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13
Q

Prostate acid phosphatase is an important

A

Tumor marker

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