Enzyme Profile In Liver Diseases Flashcards
1
Q
Alanine Aminotransferase needs —- as coenzyme
A
Pyridoxal phosphate
2
Q
Normal serum level of ALT is
A
10-30U/L
3
Q
Very high levels of ALT are seen in
300-1000U/L
A
Acute hepatitis
Viral or toxic in origin
4
Q
Both ALT and AST levels are increased but
A
ALT>AST
5
Q
Moderate increase of ALT seen in
A
Chronic liver diseases
Cirrhosis
Hepatitis c
Nonalcoholic steatohepatitis
6
Q
Nucleotide phosphatase is also known as
A
5’ nucleotidase
7
Q
NTP hydrolyses nucleotides to nucleosides at a pH of
A
7.5
8
Q
NTP is inhibited by
A
Nickel ions
But it doesn’t inhibit ALP
9
Q
NTP is an
A
Ectoenzyme
10
Q
NTP serum level is
A
2-10 IU/L
11
Q
NTP level is increased in
A
Hepatitis Biliary obstruction ( highly elevated)
12
Q
Gamma glutamyl transferase transfers ——-
A
Gamma glutamyl residues to the substrate
13
Q
GGT is used in synthesis of
A
Glutathione
14
Q
GGT has — isoenzymes
A
11
15
Q
GGT is seen in
A
Liver Kidney Pancreas Intestinal cells Prostate gland
