Prostate ca Flashcards
1
Q
Abiratarone
A
Peripheral androgen synthesis inhibitor
17CYP pathway
Inhibits 17α-hydroxylase (CYP17), key enzyme in steroid synthesis
Keyside effects
- Fluid retention, hypertension
- Hypokalemia
Must be used in combination with prednisolone
2
Q
GnRH antagonist
A
Degarelix
3
Q
GnRH agonist
A
goserelin, leuprolide
