Prostate Flashcards
High consumption of _________fats , such as _________ or _______ can cause prostate cancer.
Dietary fats, alpha linoleic acid or polycyclic aromatic hydrocarbons
Consumption of isoflavonoid genistein prevents what cancer?
Prostate
(cauliflower, cabbage, kale kind) Cruciferous vegetables with_________ is a protective factor for prostate cancer
Isothiocyanate sulforaphane
_______ found in tamotoes is a protective factor for prostate cancer
Lycopene
Is inhibitors of cholesterol biosynthesis like statin is it a protective factor for prostate cancer. True or False
True
_________ are the predominant therapies?
5 alpha reductase inhibitors
Prostate cancer occur in _______ zone?
Peripheral
PSA is increased in?
Prostate cancer, prostatitis, BPH
PSA levels are undetectable after about ___________ weeks if prostate has been completely removed.
6
95% of the prostate cancers are transitional cell tumors. True / false?
False, Adenocarcinoma
Second line screening tests for prostate cancer?
4K score
Prostate health index
CT> MRI in prostate cancer? True or false
True
T1 is inapparent tumor? True or false
True
T3- invades adjacent structures? True or False
False, T4 invades adjacent structures
T3- extends through prostate capsule and may invade seminal vesicles
T2 tumor is confined within prostate?true or false
True
After radicle surgery to removal all prostrate tissue, PSA should be undetectable in the blood within_____ weeks.
6
After radiation therapy PSA becomes undetectable? True or False?
False, PSA is still detectable after radiation therapy because the remaining non-malignant elements of the gland continue to produce PSA even if all cancer cells have been eliminated.
Do you preserve external spincter in radical prostatectomy? True or false?
True
Do you spare Autonomic nerves in radicle prostectomy? True or False?
True
Radical prostatectomy gives a life expectancy of 2 yrs? True or False
False, it gives a life expectancy of 10 yrs or more
Complications of radical prostatectomy are?
Erectile dysfunction & incontinence
Erectile function never returns after radical prostatectomy? True or False?
False, erectile function begins to return 6 months after surgery if neurovascular tissue has been preserved.
Safe administration doses_____ and resulted in higher local control rates and fewer side effects.
> 80gy
This is direct implantation of radioactive sources into the prostate.
Brachytherapy
____________is the treatment recommended to patients with cancers of low aggressiveness.
Active surveillance
What are the testosterone lowering agents given for prostate cancer?
GnRH agonists/ antagonists - leuprolide acetates and goserlin acetate
Pure GnRH antagonists - Degarelix or relugilix
17, 20-lyase inhibitors
CYP 17 inhibitors
Estrogen such as diethylstilbestrol
