prostaglandins Flashcards
1
Q
prostacyclin
A
DECREASE platelet aggregation (via increasing cAMP which inhibits thromboxane synthesis)
2
Q
Thromboxane
A
INCREASES platelet aggregation (via increased Ca2+)
3
Q
first stable product formed in prostaglandin syntheiss that is converted to toher ptostaglandins by tissue specific enzymes
A
PGH2
4
Q
anti-inflammatory steroids (glucocorticoids)
A
inhibit PLA2 (decrease PG and Leukotriene synthesis)
5
Q
NSAIDs
A
prevents synthesis of PG but NOT leukotrienes). inhibit COX
6
Q
What gets inhibited for ashtma?
A
5-lipoxygenase
