Prostaglandin

Question 1

Prostaglandin Drugs Names

Answer 1

Misoprostol

Question 2

Prostaglandin Therapeutic Actions

Answer 2

• Inhibits gastric acid secretion and increases bicarbonate and mucous production in the stomach

Question 3

Prostaglandin Indications

Answer 3

• Prevention of NSAID-induced gastric ulcers

- Treatment of duodenal ulcers

Question 4

Prostaglandin Contraindications and Cautions

Answer 4

Contraindications:
• Pregnancy

Caution:
• Lactation

Question 5

Prostaglandin DDI

Answer 5

DDI:
• Aluminum salts
• Phenytoin, fluoroquinolone, or penicillamine

Question 6

Prostaglandin Adverse Effects

Answer 6

• GI effects:
- Nausea, diarrhea, abdominal pain, flatulence, vomiting, dyspepsia, and constipation
• CNS effects:
- Miscarriages, excessive bleeding, spotting, cramping, hypermenorrhea, dysmenorrhea, and other menstrual disorders

Question 7

Prostaglandin:

Assessment

Answer 7

Assess:
Hx: Allergy, lactation and pregnancy
Physical: vital signs, lesions in or mucosa or rash, orientation, affect, and reflexes, abdominal, neurological status, respiratory status (baseline)
Labs: monitor results

Question 8

Prostaglandin:

Diagnosis

Answer 8

Dx:

• Diarrhea
• Risk for constipation
• Imbalanced nutrition: less than body requirements
• Ineffective sexuality pattern
• Deficient knowledge

Question 9

Prostaglandin:

Implementation

Answer 9

Implementation:
• Administer to patients at high risk for NSAID-induced ulcers during the full course of NSAID therapy
• Evaluate nutritional status
• Arrange for a serum pregnancy test within 2 weeks before beginning treatment and begin therapy on the 2nd or 3rd day of the menstrual period
• Provide the patient with information regarding the associated risks of pregnancy
• Explain the risk of menstrual disorders and pain, miscarriage, and excessive bleeding
• Provide thorough patient teaching

Question 10

Prostaglandin:

Implementation

Answer 10

Eval:
Response to the drug 
Adverse effects
 Effectiveness of comfort measures
Compliance with regimen
Effectiveness of teaching plan