Properties Of Sensory and Motor Neuronz Flashcards
What are passive electrical properties of neurons
Wires conduct current by electron Flow, neurons conduct current by ion flow, in both cases, current flow is impeded by resistance
Neuron can be modelled as a wire
.each segment in model has a resistance
.this causes an applied voltage to decay as it travels along neuron
.ultimately the voltage will decay to zero
How do we define the decay of the voltage
By 2 peramiters
1.space constant (how far the voltage travels)
2.time constant (how fast)
Describe passive conduction velocity
Anything that increases the space constant or reduces the time constant will therefore increase conduction velocity
What is the voltage across a cell membrane determined by
A balance between electrical charge and osmotic force i.e balance between electrical charge and osmotic force
Describe chemical and electrical gradients
- Net extrecellular positive charge under resting condition
2.hyper polarisation increases this potential (action potential less likely)
3.de polarisation reduces potential (making action potential more likely)
What is the sodium pump crucial for
Establishing the membrane potential necessary for the action potential.
Otherwise sodium and potassium would leak across the membrane, causing the potential to drop to zero
Describe action potential: voltage-gated ion channels
1.Ap is mediated by voltage gated ion channels embedded in cell membrane
2.open when a threshold is reached
3.sodium and potassium channels are the primary mediators of action potential
Sodium channel has 3 states:
1.open
2.closed
3.deactivated
Potassium channel has 2 states:
1.open
2.closed
What is the action potential positive feedback cycle
1.cell membrane becomes depolarised
2.once depolarisation reaches a thresh hold sodium channels open
3.causes more sodium to pass through the osmotic gradient and leads to more depolar
4.this opens all adjacent channels causing a chain reaction
5.potassium channels open more slowly and this resulting outflow repolarises membrane potential
6.sodium channels close and temporarily deactivated
What different dynamics do sodium and potassium channels have
Na channels open quickly, K channels open more slowly, and this difference is crucial for action potential
What does the refractory period do
Prevents the positive feedback continuing indefinitely, this ensures the action potential travels in one direction
What are the effects of neuron diameter
Time constant is barely affected
Space constant becomes larger therefore a faster space constant
What is myelin
Essentially an insulator wrapped around the axon and neuron