properties of drug classes Flashcards
1
Q
what [] are b lactams considered cidal at
A
time dependent!
if immune- competent >50%
if immunocompromised >90%
2
Q
which protein MOA drug class is cidal
A
aminoglycosides
3
Q
aminoglycosides are [] dependent at _____ MIC
A
10x MIC
4
Q
what are the ratios for FQ G- and G+ coverage
A
G- 100x AUC:MIC
G+ 50x AUC:MIC
5
Q
what drugs accumulate intracellularly
A
tetracyclines, macrolides, phenicols
