general things

Question 1

go to UTI drug in uncomplicated cases

Answer 1

amoxicillin

Question 2

superficial pyoderma drugs

Answer 2

cephalexin, clindamycin, clavamox

Question 3

rickettsial disease

Answer 3

doxycycline

Question 4

what drugs will kill a horse

Answer 4

clindamycin, doxycycline IV

Question 5

how do we dose aminoglycosides

Answer 5

SID no matter what because of concentration dependent renal toxicity

Question 6

small animal URT drug

Answer 6

macrolides - erythromycin

Question 7

bite wounds?

Answer 7

clindamycin

Question 8

drugs to be careful in cats

Answer 8

chloramphenicol. bone marrow supression

Enrofloxacin- blindness > 5mg/kg

Question 9

broad spectrum that gets staphs and can use in utis

Answer 9

clavamox

Question 10

best 3rd gen for anaerobes

Answer 10

cefovecin

Question 11

aminoglycosides are what coverage

Answer 11

G-
aerobes
staphs

Question 12

MOA for B lactams

Answer 12

cell wall inhibition

Question 13

what is the coverage of clavamox

Answer 13

streps, staphs, anaaerobes, clostridium

Question 14

used for pre and intra op antimicrobial prophylaxis

Answer 14

cefazolin

Question 15

considered the most active 3rd gen ceph, covers staph, strep, G-

Answer 15

cefpodoxime proxetil

Question 16

when can we not use cefpodoxime proxetil

Answer 16

most anaerobes and ESBL bacti

Question 17

brand name of cefovecin

Answer 17

convenia

Question 18

when should we not use cefovecin

Answer 18

severe systemic infections, ESBL, MRS

Question 19

what can you not use aminoglycosides for

Answer 19

streps and anaerobes

Question 20

when do we reach for aminoglycosides

Answer 20

severe infection, G- enteric bacti

Question 21

what things to remember about aminoglycosides

Answer 21

inactivated by pus, nephrotoxic, always SID, not absorbed PO

Question 22

what is the MOA for fluoroquinolones

Answer 22

DNA gyrase inhibitors

Question 23

what to remember about fluoroquinolones/enrofloxacin

Answer 23

cartilage toxicity and ocular toxicity/retinal degeneration >5mg/kg in cats

Question 24

when do we use tetracyclines

Answer 24

rickettsial disease, intracellular diseases

Question 25

which tetracycline is the most lipophilic

Answer 25

doxycycline

Question 26

the MOA for potentiated sulfonamides

Answer 26

folic acid pathway inhibitors

Question 27

in general what do we use sulfas for

Answer 27

empiric treatment of mild or superficial infections, wounds, UTI

Question 28

adverse effects of sulfas in small animals

Answer 28

a lot. polyarthropathy, lymphadenopathy, fever, focal retinitis, KCS, mucosal ulceration, hypothyroidism, anemia

Question 29

MOA for nitromidazoles

Answer 29

inhibits protein synthesis through intrabacterial production of toxic metabolites.

Question 30

what do we use nitromidazoles for

Answer 30

anaerobes, clostridia, giardia

Question 31

what do we use amphenicols for

Answer 31

abscesses where drainage isnt possible

Question 32

adverse effects of chloramphenicol

Answer 32

reversible bone marrow supression. aplastic anemia in humans

Question 33

why cant you give lincosamides to a horse

Answer 33

fatal bloody diarrhea

Question 34

when do we use lincosamides

Answer 34

in abscesses where drainage isnt possible. no G- infections

Question 35

coverage of macrolides

Answer 35

G+, intracellular, pneumonia, abscesses

Question 36

what do we use macrolides in horses for

Answer 36

R. equi in foals

Question 37

which tetracycline crosses the bbb best

Answer 37

minocycline