proliferation, remodelling and management Flashcards
1
Q
when does proliferation occur?
A
- 1 to 10 days
2
Q
what is attracted to injured area and when ?
A
- fibroblasts attracted to area 24 hours post exercise
3
Q
what do fibroblasts do?
A
- fibroblasts degrade fibrin and replaces it with extracellular matrix
4
Q
what two processes does extracellular matrix signal?
A
- angiogenesis
- granulation
5
Q
what does proliferation produce?
A
- collagen
- glycoproteins
- hyaluronic acid
6
Q
what are the nine influencing factors on proliferation?
A
- severity of trauma
- early management
- tissue vascularity
- age
- nutrition
- medication
- temperature
- biochemical factors
- appropriate loading
7
Q
what capacity does muscles have? - describe
A
- regenerative capacity
- MuSC - myoblast- myocyte - myotube - myofiber
8
Q
when does remodelling process occur?
A
- 10 days + post injury
9
Q
what does remodelling involve?
A
- ongoing fibroblast activity and collagen production
10
Q
when does remodelling peak?
A
- peaks at 2-3 weeks following injury
11
Q
what does remodelling absorb and deposit?
A
- absorption of older fibrous tissue
- deposition of new fibrous tissue
12
Q
what contracts in the remodelling phase?
A
- scar tissue contraction
13
Q
what are type III collagen fibres replaced with?
A
- replaced with type I collagen fibres
14
Q
how do physios manage healing tissues?
A
- make sure there are no contrary influences
- all possible favourable conditions are encouraged
15
Q
do all injuries recover in the same amount of time?
A
- different injuries take different periods of time to recover
- muscles recover quicker than ligaments and tendons due to higher blood supply and content of cells that repair