Proliferación y crecimiento celular 2 Flashcards

1
Q

Factor interno inductor del ciclo celular

A

CDK-CICLINAS: fosforilan

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2
Q

Función de los complejos inhibidores (Cki)

A

Inhiben directamente cdk-ciclina

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3
Q

CIP

A

P21 y P27

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4
Q

Tipos de complejos inhibidores (Cki)

A

CIP
INK

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5
Q

INK

A

P16 (solo CDK4 y 6) Cdk G1 con ciclina D

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6
Q

Para el ciclo celular ante un daño al ADN.
Se activa por fosforilación provocado por proteínas.
Induce apoptosis.

A

P53

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7
Q

Función de E2F

A

Induce la transcripción de genes necesarios para la síntesis de ADN

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8
Q

Rb (retinoblastoma) inhibe:

A

Factor E2F

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9
Q

Estimulan la mitosis (factor de crecimiento derivado de plaquetas-PDGF y factor de crecimiento epidérmico-EGF)

A

Mitógenos

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10
Q

Causan un aumento en el tamaño celular al aumentar la síntesis proteica (factor de crecimiento nervioso-NGF t PDGF)

A

Factores de crecimiento

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