Prokaryotic cell division Flashcards
What is FtsZ
Bacterial analogue of tubulin, forms division septum for bacterial cells, spiral filament that forms a ring in the midcell to recruit other proteins to form division septum
Forms Z-ring
What does the oscillating Min system do
helps select the site of FtsZ ring formation, setus up a gradient of Min C
What is MinC and where is it highest and lowest
Inhibits the FtsZ ring formation, lowest in the middle, highest in the end
What is the bacterial nucleoid and what does it do
The bacterial chromosome with its many associated proteins are collectively referred to as the bacterial nucleoid
The presence of the nucleoid also inhibits FtsZ ring formation. Therefore the division septum cannot be formed until the daughter chromosomes are produced and moved away from midcell preventing the septum from chopping the developing daughter chromosomes
E.coli cell division is driven by _____ ______ _____
protein gradient formation
MinDE oscillation studies are difficult to relate back to living cells, what is the solution?
Established an in vitro visualization system with membranes in a cell-shaped compartment
does length affect oscillation
longer compartments establish multiple Min oscillatory periods within the compartment
Why do cocci bacteria not have a min system
Can’t define poles
What is a Min system
a system of 3 proteins (MinCDE) that establish a pole to pole oscillation in cells to provide an inhibitory signal to Z-ring formation at the cell poles
