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Lucy Knox - Year 3 > Progress test > Flashcards

Progress test Flashcards

1
Q

What is the target of Infliximab?

A

A chimeric antibody against TNF-alpha

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2
Q

What is a standard fluid you might give to an unwell patient in hospital?

A

0.9% NaCL

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3
Q

A lady has been in a RTA and is unconscious. Surgery is needed. Do you…

  • Get the consultant to consent for her
  • Ask her next of kin to consent
  • Wait until she responds
  • Do the surgery without consent
A

No consent needed

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4
Q

What neurotransmitter is implicated in OCD?

A

Serotonin = 5 HT

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5
Q

What effect does Clarithromycin have on a patient taking warfarin?

A

Increases anticoagulant effect - INF increase - Increase bleeding risk

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6
Q

What drug type is haloperidol?

A

Anti-psychotic

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7
Q

Why might someone on anti-psychotics be given Procyclidine?

A

An anti-cholonergic.

To treat drug induced Parkinsonian and Akathisia side effects of anti-psychotics.

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8
Q

What is in the morning after pill?

A

high dose oral progesterone

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9
Q

A patient has psoriasis. Name 3 signs you might find.

A

Plaques
Swelling joints
Nail dystrophy - pitting, onchylysis

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10
Q

If a patient has persistent swallowing problems, what is a good investigation?

A

Upper GI endoscopy

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11
Q

If someone has a thyroid problem, which is the most useful thryoid level to test?

A

Plasma TSH

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12
Q

A patient has had an MI and is now in complete heart block. Which vessel is affected?

A

Right coronary

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13
Q

Someone has Left visual field loss in both eyes, but the centre of their vision is ok. Where is the damage?

A

R occipital lobe

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14
Q

On biopsy if the liver this is seen, what is the disease?

Multiple epitheloid granulomata and ventral acellular necrosis.

A

TB liver

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15
Q

What is the risk to the newborn of taking fluoxetine in pregnancy?

A

Persistent pulmonary hypertension of the newborn.

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16
Q

What is effected in haemophilia A?

A

a deficiency in functional factor VIII - so it can’t activate Factor X.

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17
Q

What clotting test will be prolonged in Haemophilia A?

A

APTT will be prolonged

18
Q

What should you do if someone presents with a breast lump?

A

A triple assesment - Examination, imaging (mammography of US of under 35), fine needle biopsy

19
Q

What is a probable side effect if someone is having radiotherapy to their bronchus?

A

Oesophagitis

20
Q

What is Olanzapine for?

A

Anti-psychotic used in Schizophrenia.

21
Q

A patient takes Olanzapine for the first time, he becomes feverish, he develops muscle rigidity and his conscious level is impaired. You notice he has also become incontinent. What complication has he developed?

A

Neuroleptic malignant syndrome.

22
Q

An 8 year old with pneumonia. What is a common bacterial causative agent?

A

Strep Pneumoniae

23
Q

When someone is warfarinised, what is a usual INF target?

A

2.5

24
Q

For what conditions might you so a plasma cortisol and an adrenocorticotropic hormone (ACTH) level test?

A 
Cushings disease (high, high)
Adrenal tumour (High, low ACTH)
Addisons disease (low cortisol, high ACTH)
Hypopituitiarism (low, low)
25
Q

What is the risk of relapse of thyrotoxicosis after successful treatment and stopping medication?

A

50%

26
Q

What is the indication of an endarterectomy?

A

90% occlusion of the carotid

Symptoms of curtain coming down over the eye

27
Q

What hormone can be tested to indicate the menopause?

A

FSH level is high

28
Q

What are high levels of Anti-neutrophil cytoplasmic antibodies (ANCAs) associated with?

A

Systemic vasculitis, small vessel vasculitis, eg. Wegners.

29
Q

A patient with renal artery stenosis will have what changes to pasma renin activity?

A

Activity will be increased

30
Q

A patient has weakness of wrist extension and reduced sensation to the back of their hand between the thumb and index finger. What nerve may be injured?

A

Radial nerve

31
Q

A patient has diarrhoea. She has just returned from Thailand. Her Hb is low, and eosinophils are high. What may be the causitive agent?

A

A Hookworm

32
Q

A lady 38 weeks gestation has severe pre-eclampsia. What is the management?

A

Mg sulphate - reduce seizure risk

Delivery of baby

33
Q

What are the catagorise of GCS?

A 
Eyes:
Spontaneous - 4
To sound - 3
To pressure - 2
None - 1
Verbal:
Orientated - 5
Confused - 4
Words - 3
Sounds - 2
None - 1
Motor:
Obey commands - 6
Localising - 5
Normal flexion - 4
Abnormal flexion - 3
Extension - 2
None - 1
34
Q

What process is increased in diabetic ketoacidosis?

A

Increased lipolysis

35
Q

What is a hormonal side effect of carbamazipine?

A

Can cause SIADH

An anticonvulsant

36
Q

Someone has ?SAH. The CT head taken rapidly looks ok. What do you do next?

A

Do a LP

37
Q

A patient with HIV has a very low CD4 count. There is a mass in the brain. What may be causing it?

A

Primary cerebral lymphoma

38
Q

What can occur if sodium valporate is taken in pregnancy?

A

Spina bifida

39
Q

What is wrong and what is the treatment?

Pt presents with throbbing head ache, they have pulsatile temporal arteries. They have a raised ESR.

A

Temporal arthritis

Predinisalone

40
Q

A fracture to the anterior or posterior ribs most suggests non accidental injury?

A

Posterior ribs.

41
Q

A diabetic with cellulitis is most likely infected with what organism?

A

Step Pyogenes

42
Q

What may someone with uncontrolled coeliac disease be more at risk of?

A

Small bowel lymphoma

Lucy Knox - Year 3 (2 decks)

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