Problems With Synapses 3 Flashcards
What are 3 ways neurotransmitters are removed
3 ways neurotransmitters are removed are:
Reuptake of neurotransmitter in presynaptic membrane
Neurotransmitter broken down by enzymes
Neurotransmitter diffuses away from synapse
What is antagonist
Antagonists are molecules that bind to receptors but don’t stimulate them, blocking action potentials
How does MDMA work
MDMA work by blocking pre synaptic receptors and stimulating release of serotonin, so more action potentials are produced
How does low serotonin levels affect transmission of impulses
Low serotonin levels affects transmission of impulses in brain by:
Serotonin is neurotransmitter, there will be less
Less neurotransmitter results in fewer depolarisations of post synaptic membranes
So less chance of action potential
How can MDMA lead to depression
MDMA can lead to depression by:
MDMA use results in depletion of serotonin
Post synaptic membrane becomes less responsive to serotonin
Lack of serotonin associated with depression