Problems in Pregnancy Flashcards

1
Q

What is pre-eclampsia

A

new HT presenting after 20 weeks gestation with significant proteinuria

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2
Q

Symptoms of pre-eclampsia

Signs

A
severe headaches 
visual problems (blurry, flashing lights, double vision)
persistent new epigastric pain 
vomiting 
breathlessness
sudden swelling of face, hands, feet
Signs:
liver tenderness
low platelet count 
abnormal ALT or AST 
clonus 
HELLP (haemolysis, elevated liver enzymes, low platelets) 
pailloedema 
reduced foetal movements
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3
Q

Urgent obstetric admission if: (pre-eclampsia)

A

new HT after 20 weeks
+ urine dipstick protein
or pre-eclampsia symptoms
or BP 160/110

(other women with new HT, seek urgent specialist advice)

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4
Q

First line treatment for pre-eclampsia

Second line

A

labetalol 100mg 2x

methyldopa or nifedipine

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5
Q

What is eclampsia

A

pre-eclampsia plus ne or more seizures

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6
Q

Risk Factors for gestational diabetes

A
previous history of GDM
BMI >30
prev baby weighing 4.5kg+
FH of type 2 or GDM 
south asian/black caribbean/middle eastern 
PCOS
previous stillbirth
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7
Q

what is OGTT

A

oral glucose tolerance test: offered to women with risk factors for GDM between 24-28 weeks (bloods taken at fasting and 2 hours after glucose load)

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8
Q

when should hyperemesis gravidarum have ceased?

A

week 20

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9
Q

common hyperemesis gravidarum presentation

A

persistent vomiting
weight loss
dehydration and electrolyte imbalance
ketouria (<2+ ketones)

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10
Q

Management of hyperemesis gravidarum

A
avoid food/smells triggers
eat plain crackers in AM 
eat blank, small, frequent, meals low in carb and fat but high protein 
ginger
acupressure
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11
Q

(hyperemesis gravidarum)

seek urgent medical care if:

A

very dark urine, or no urination for 8+ hours

abdo pain

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12
Q

If anti-emetic required in pregnancy, give what

A
antihistamine (cyclizine or oral promethazine)
or prothiazine (oral prochlorperazine)
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13
Q

oral metclopamide and ondanzetron shouldn’t be prescribed to pregnant women for longer than 5 days - why?

A

Long QT syndrome

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14
Q

How many appointments would someone be offered for first pregnancy vs subsequent?

A

10 vs 7

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15
Q

Who should be given anti-D?

A

all Rhesus D neg women who don’t have immune anti-D during 3rd trimester

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16
Q

2 vaccinations offered to everyone during pregnancy?

A
seasonal flu 
whooping cough (between 16-32 weeks)
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17
Q

When is first USS pregnant?

A

10-13 weeks

  • checks gestational age
  • detect multiple pregnancies
  • confirm viability
  • detect gross foetal abnormalities
  • provide component of Down’s screening if desired (via nuchal translucency measurement)
18
Q

Next USS offered?

A

at 18-20 weeks

  • to reassure no gross structural abnormalities
  • to determine placental morphology and localisation
  • confirm foetal growth appropriate
19
Q

How is foetal growth monitored?

A

symphysis-fundal height poltting

20
Q

Pre-eclampsia risk factors

A
40 or older
nulliparity
interval of 10 years pregnant
FH 
Previous Hx 
BMI >30
Pre-existing vascular disease (eg. HT)
pre-existing renal disease
diabetes 
lupus or antiphospholipid syndrome
multiple pregnancy
21
Q

Screen for pre-eclampsia at every appointment how

A

BP

urinalysis

22
Q

What effect can NSAIDs have on foetus in third trimester?

A

premature closure of ductus arteriosus

23
Q

is the cut off for anaemia in pregnancy lower/higher in third trimester?

A

lower (105)

1/2nd: 110

(Normal 120)

24
Q

2 physiological changes to urogenital tract in pregnancy

what resultant effect does this have

A

bladder volume increases
detrusor tone decreases

= increased urinary stasis,. compromised ureteric valves, vesicoureteric reflux
= increased UTI risk

25
Which organism accounts for most UTIs?
E. coli
26
What is acute cystities?
dysuria, frequency, urgency and suprapubic pain withOUT systemic illness often in women with asymptomatic bacteriuria
27
Treating acute cystities
hydration and antibiotics
28
Pyelonephritis is infection of what
renal papilla
29
Symptoms of pyelonephritis
like acute cystities but with sepsis (tachycardia, hypotension, tachyapnoea, pyrexic) loin pain urinary symptoms
30
Investigations for pyelonephritis
``` MSU USS of renal tract FBC Renal function tests blood culture CRP ```
31
Name 3 causes of bleeding in early pregnancy
- implantation bleeding (physioloigcal) - miscarriage - ectopic pregnancy - cervical causes (Ectropon/polyp, cancer) Colar pregnancy
32
Types of miscarriage (pre 22 weeks)
threatened - if pregnancy remains viable missed - if nonviable incomplete - products of conception partly expelled complete - products completely expelled recurrent - 3 or more consecutive
33
Medical / Surgical management of miscarriage
MEdical: mifepristone and misoprostal Surgical: evacuation of uterus by suction evacuation or curettage
34
Hydatiform mole Signs Diagnosis
growth of an abnormal fertilized egg or an overgrowth of tissue from the placenta - bleed early - expulsion of grape like tissues - pregnancy symptoms HIGH levels of beta hCG and confirmed by histology
35
Definition of antepartum haemorrhage
bleeding from genital tract after 22nd week of pregnancy
36
Name 3 causes of antepartum haemorrhage
``` placental abruption placenta pravaeia cervicitis trauma vasa previa vulvo-vaginal varicosities genital tumours infection ```
37
Define placenta praevia
(partly or completely inserted in lower uterine segment) | grades 1-4
38
Define placenta abruption
bleeding after premature separation of normally situated placenta can be revealed or conceleaed (if obvious bleed/not)
39
Define preterm labour
before 37 weeks
40
Risk factors for preterm labour
multiple pregnancies Hx of preterm labour polyhydramnios infection
41
3 things may be given to manage preterm labour
tocolysis (to slow labour to administer steroids and in-utero transfer) steroids (for foetal lung amturation) magnesium sulphate (for neuro protection)
42
What is obstetric cholestasis
pruritus (often hands/feet) in absence of skin rash with abnormal liver function tests (both resolve after birth)